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Merck
CN

138M-1

CD138/syndecan-1 (B-A38) Mouse Monoclonal Antibody

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
B-A38, monoclonal
Application:
immunohistochemistry (formalin-fixed, paraffin-embedded sections)
Species reactivity:
human
Citations:
10
Technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:200

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biological source

mouse

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

B-A38, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (138M-14)
vial of 0.5 mL concentrate (138M-15)
bottle of 1.0 mL predilute (138M-17)
vial of 1.0 mL concentrate (138M-16)
bottle of 7.0 mL predilute (138M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:200

isotype

IgG1

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Quality Level

100
500

Gene Information

human ... SDC1(6382)

相关类别

Analysis Note


IVD
IVD
IVD
RUO

General description

CD138, Syndecan 1, is a transmembrane heparan sulfate proteoglycan, present mainly in a variety of epithelial tissues, participating in cell proliferation, cell migration, intercellular communication, and cell-matrix interactions. In lymphoid tissues, CD138 is expressed in the late stages of B-cell differentiation with progression towards plasma cells. Anti-CD138 is a good marker to selectively identify plasma cells, benign or malignant, in lymphoid tissues CD138 is also expressed in a variety of epithelial cells.

Other Notes

CD138/syndecan-1 Positive Control Slides, Product No. 138S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000474126
0000474126
0000466478
0000466478
0000460495

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WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 254-254 null
A Oksanen et al.
Journal of clinical pathology, 58(4), 376-381 (2005-03-26)
Both Helicobacter pylori and gastro-oesophageal reflux disease (GORD) may cause inflammation in cardiac mucosa. Intestinal metaplasia (IM) is found more often in GORD associated inflammation than in inflammation caused by H pylori, especially in young individuals. To examine morphological differences
Said J, et al.
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 261-261 null
Said J, et al.
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 261-261 null
I B Bayer-Garner et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 14(10), 1052-1058 (2001-10-13)
Syndecan-1 (CD138) mediates myeloma cell adhesion, and loss of syndecan-1 from the cell surface may contribute to myeloma proliferation and dissemination. Flow cytometry analysis of myeloma cells in bone marrow specimens shows heterogeneity in cell surface syndecan-1 expression. It is
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