跳转至内容
Merck
CN

14202

二异丙基氟磷酸酶

≥30 U/mg

登录 查看组织和合同定价。

选择尺寸


关于此项目

化学文摘社编号:
MDL编号:
UNSPSC代码:
12352204
NACRES:
NA.54
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

生物来源

fermentation/recombinant

质量水平

表单

lyophilized solid

比活

≥30 U/mg

储存温度

−20°C

包装

无底玻璃瓶。内含物装在锥底内插管中。

其他说明

一个单位对应于在 pH 8.1 和 22 °C 下每分钟水解 1 μmol 氟磷酸二异丙酯的酶量

象形图

Health hazard

警示用语:

Danger

危险声明

预防措施声明

危险分类

Resp. Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Jürgen Gäb et al.
Analytical and bioanalytical chemistry, 396(3), 1213-1221 (2009-11-28)
The enzyme diisopropyl fluorophosphatase (DFPase, EC 3.1.8.2) from the squid Loligo vulgaris effectively catalyzes the hydrolysis of diisopropyl fluorophosphate (DFP) and a number of organophosphorus nerve agents, including sarin, soman, cyclosarin, and tabun. Until now, determination of kinetic data has
Marc-Michael Blum et al.
Biochemistry, 47(18), 5216-5224 (2008-04-10)
A wide range of toxic organophosphorus pesticides and nerve agents is effectively hydrolyzed by the structurally related phosphotriesterase enzymes paraoxonase (PON1) from human plasma and diisopropyl fluorophosphatase (DFPase) from the squid Loligo vulgaris. Both enzymes have potential use as medical
Debra A Gearhart et al.
Toxicology and applied pharmacology, 218(1), 20-29 (2006-11-25)
Diisopropylfluorophosphate, originally developed as a chemical warfare agent, is structurally similar to nerve agents, and chlorpyrifos has extensive worldwide use as an agricultural pesticide. While inhibition of cholinesterases underlies the acute toxicity of these organophosphates, we previously reported impaired axonal
Marc-Michael Blum et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(3), 713-718 (2009-01-13)
Hydrogen atoms constitute about half of all atoms in proteins and play a critical role in enzyme mechanisms and macromolecular and solvent structure. Hydrogen atom positions can readily be determined by neutron diffraction, and as such, neutron diffraction is an
Julian C H Chen et al.
Acta crystallographica. Section D, Biological crystallography, 66(Pt 11), 1131-1138 (2010-11-03)
Diisopropyl fluorophosphatase (DFPase) is a calcium-dependent phosphotriesterase that acts on a variety of highly toxic organophosphorus compounds that act as inhibitors of acetylcholinesterase. The mechanism of DFPase has been probed using a variety of methods, including isotopic labelling, which demonstrated

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持