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14871

BICINE

Name: BICINE
Brand: SIGMA

BioUltra, ≥99.5% (T)

别名:

N,N-双(2-羟乙基)甘氨酸

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关于此项目

经验公式（希尔记法）:

C₆H₁₃NO₄

化学文摘社编号:

150-25-4

分子量:

163.17

EC Number:

205-755-1

UNSPSC Code:

12161700

PubChem Substance ID:

57647225

Beilstein/REAXYS Number:

1769362

MDL number:

MFCD00004295

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product line

BioUltra

assay

≥99.5% (T)

form

powder or crystals

impurities

insoluble matter, passes filter test

ign. residue

≤0.1%

loss

≤0.1% loss on drying, 20 °C (HV)

pH

4.0-5.5 (25 °C, 1 M in H₂O)

useful pH range

7.6-9.0

pKa (25 °C)

8.3

solubility

H₂O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl^-): ≤50 mg/kg, sulfate (SO₄^2-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤20 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

1 M in H₂O

UV absorption

λ: 260 nm A_max: 0.070, λ: 280 nm A_max: 0.040

SMILES string

OCCN(CCO)CC(O)=O

InChI

1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11)

InChI key

FSVCELGFZIQNCK-UHFFFAOYSA-N

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Application

用于低温生化工作的推荐缓冲液。用于制备稳定的血清鸟嘌呤酶测定底物溶液。通过等发色团法，使用葡聚糖凝胶^® ，作为间隔区分离血浆蛋白。

BICINE can be used to study biological buffers and zwitterionic compounds. N,N-Bis(2-hydroxyethyl)glycine has been used in a study that characterized refined crystal structures of human Ca2+/Zn2+-binding S100A3 protein. N,N-Bis(2-hydroxyethyl)glycine has also been used in a study to inform F1 antigen assembly.

Legal Information

Sephadex is a registered trademark of Cytiva

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Refined crystal structures of human Ca(2+)/Zn(2+)-binding S100A3 protein characterized by two disulfide bridges.

Masaki Unno et al.

Journal of molecular biology, 408(3), 477-490 (2011-03-08)

S100A3, a member of the EF-hand-type Ca(2+)-binding S100 protein family, is unique in its exceptionally high cysteine content and Zn(2+) affinity. We produced human S100A3 protein and its mutants in insect cells using a baculovirus expression system. The purified wild-type

The myosin dimer: an intermediate in the self-assembly of the thick filament of vertebrate skeletal muscle.

J S Davis et al.

FEBS letters, 140(2), 293-297 (1982-04-19)

Mechanism of mercury(II) reductase and influence of ligation on the reduction of mercury(II) by a water soluble 1,5-dihydroflavin.

E Gopinath et al.

Proceedings of the National Academy of Sciences of the United States of America, 86(9), 3041-3044 (1989-05-01)

The nature and rate of reduction of Hg2+ to Hg0 by 1,5-dihydro-3,(3-sulfopropyl)lumiflavin (FIH2) in buffered aqueous solutions (pH 4.7) is dependent on the ligation of Hg2+. In the presence of N,N-bis(2-hydroxyethyl)glycine or when ligated to ethylenediaminetetraacetic acid, the reduction is

Impact of ligand protonation on higher-order metal complexation kinetics in aqueous systems.

Raewyn M Town et al.

The journal of physical chemistry. A, 112(12), 2563-2571 (2008-03-04)

The impact of ligand protonation on the complexation kinetics of higher-order complexes is quantitatively described. The theory is formulated on the basis of the usual situation for metal complex formation in aqueous systems in which the exchange of water for

Irradiation inactivation analysis of acetylcholinesterase and the effect of buffer salts.

D Parkinson et al.

Radiation research, 90(2), 252-259 (1982-05-01)

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