biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
2f2, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (161M-14), vial of 0.5 mL concentrate (161M-15), bottle of 1.0 mL predilute (161M-17), vial of 1.0 mL concentrate (161M-16), bottle of 7.0 mL predilute (161M-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
isotype
IgG1
control
bone marrow
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... ITGB3(3690)
General description
CD61 also known as integrin beta chain beta 3 (ITGB3) is an integrin cell-surface protein associated with cellular adhesion and cell-surface mediated signaling. Immunohistochemical staining for CD61 can be useful in evaluating normal and abnormal megakaryocytes, which can aid in the identification of some hematopoietic malignancies. Anti-CD61 reactivity is also seen in platelets, osteoclasts, and macrophages.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
CD61 Positive Control Slides, Product No. 161S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
D Campana et al.
Leukemia, 4(9), 620-624 (1990-09-01)
During the diagnostic investigation of 750 acute leukemias, nine cases were morphologically, cytochemically, and phenotypically undifferentiated. In seven of these cases the blasts were class II+, CD34+ and TdT+, in one were class II+, TdT+, CD7+ while in the remaining
S B Fox et al.
Histopathology, 17(1), 69-74 (1990-07-01)
Megakaryocytes in 63 bone marrow trephine biopsies were examined for their staining characteristics, location and size distribution using the monoclonal antibody Y2/51 directed against platelet glycoprotein IIIa (CD61). Megakaryocytes in normal bone marrow were evenly distributed and demonstrated homogeneous staining
J Thiele et al.
Virchows Archiv. B, Cell pathology including molecular pathology, 58(4), 295-302 (1990-01-01)
To determine the number of megakaryocyte precursors (pro- and megakaryoblasts), an immunomorphometric study was performed on paraffin-embedded trephine biopsies of the bone marrow using a monoclonal antibody against platelet glycoprotein IIIa. Eighteen control specimens from patients with no evidence of
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 161M-15 | 0841683125228 |
| 161M-16 | 0841683125235 |
| 161M-16-RUO | 04061836539771 |
| 161M-18 | 0841683125259 |
| 161M-14 | 0841683125211 |
| 161M-17 | 0841683125242 |