质量水平
表单
powder
质量
purified
杂质
≤1.0% water
pH值（酸碱度）
5.0-7.5
溶解性
soluble, clear, colorless
痕量阳离子
Al: ≤5 mg/kg
As: ≤0.05 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤1000 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg
紫外吸收
λ: 260 nm Amax: ≤0.3
λ: 280 nm Amax: ≤0..2
适用性
no residue for filter test
储存温度
2-8°C
SMILES字符串
O2C(C2)C.O1CC1
InChI
1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChI key
RVGRUAULSDPKGF-UHFFFAOYSA-N
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一般描述
泊洛沙姆407是一种水溶性非离子表面活性剂，具有低毒性和良好的增溶能力。这种三嵌段共聚物由疏水的聚氧丙烯（POP）残基和两侧亲水的聚氧乙烯（POE）单元组成。
应用
泊洛沙姆407已被用于：
- 作为脂蛋白脂肪酶活性的抑制剂，以评估小鼠肝脏极低密度脂蛋白 (VLDL)-甘油三酯(TG)的分泌
- 用于小鼠VLDL分泌测定
- 溶解在磷酸盐缓冲盐水(PBS)中，通过腹膜内注射进小鼠以产生肝甘油三酯
生化/生理作用
泊洛沙姆407 （P407）在特定的聚合物浓度和温度以上表现出可逆的胶凝特性。泊洛沙姆407-基无菌注射制剂是药物传递的优秀候选物。P407热敏水凝胶广泛用作粘膜药物传递系统，因为它们不会刺激粘膜。P407被美国食品和药物管理局(FDA)称为“非活性成分”，适用于多种药物产品，如口服溶液、悬浮液和吸入制剂。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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