主要文件

查看所有文档

16842

Sodium (S)-β-hydroxyisobutyrate

Name: Sodium (<I>S</I>)-β-hydroxyisobutyrate
Brand: SIGMA

≥96.0%

别名:

(S)-β-Hydroxy-isobutyric acid sodium salt, (S)-3-Hydroxy-2-methylpropionic acid sodium salt, S-HIBA, R-β-HIBA-Na, Sodium (S)-3-hydroxy-2-methylpropionate

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₄H₇NaO₃

化学文摘社编号:

1893416-17-5

分子量:

126.09

NACRES:

NA.25

PubChem Substance ID:

329751395

UNSPSC Code:

12352106

MDL number:

MFCD17215930

Assay:

≥96.0% (GC), ≥96.0%

Quality level:

100

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

Quality Level

100

assay

≥96.0% (GC), ≥96.0%

optical purity

enantiomeric excess: ≥98.0%

composition

sodium, 17.5-19.0%

storage temp.

2-8°C

SMILES string

[Na+].C[C@@H](CO)C([O-])=O

InChI

1S/C4H8O3.Na/c1-3(2-5)4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1/t3-;/m0./s1

InChI key

RBJZIQZDAZLXEK-DFWYDOINSA-M

说明

Application

3-Hydroxyisobutyrate (HIBA) may be used to study the distribution, characterization and kinetics of enzymes involved in branched chain amino acid metabolism such as 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31) and 3-hydroxyisobutyryl-CoA hydrolase (EC: 3.1.2.4). (S)-β-hydroxyisobutyrate may be used in stereospecific studies.

Biochem/physiol Actions

Metabolite in valine, leucine and isoleucine degradation, a reactant of enzymes 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31), 3-hydroxyacyl-CoA dehydrogenase (EC: 1.1.1.35) and 3-hydroxyisobutyryl-CoA hydrolase (EC: 3.1.2.4). Enantiomeric ratio can be used in diagnosis of metabolic diseases, e.g. 3-hydroxyisobutyric aciduria.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

1448202

1448202V

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Mutations in the gene encoding 3-hydroxyisobutyryl-CoA hydrolase results in progressive infantile neurodegeneration.

Ference J Loupatty et al.

American journal of human genetics, 80(1), 195-199 (2006-12-13)

Only a single patient with 3-hydroxyisobutyryl-CoA hydrolase deficiency has been described in the literature, and the molecular basis of this inborn error of valine catabolism has remained unknown until now. Here, we present a second patient with 3-hydroxyisobutyryl-CoA hydrolase deficiency

Expression of 3-hydroxyisobutyrate dehydrogenase in cultured neural cells.

Radovan Murín et al.

Journal of neurochemistry, 105(4), 1176-1186 (2008-02-21)

The branched-chain amino acids (BCAAs)--isoleucine, leucine, and valine--belong to the limited group of substances transported through the blood-brain barrier. One of the functions they are thought to have in brain is to serve as substrates for meeting parenchymal energy demands.

Stereodifferentiation of 3-hydroxyisobutyric- and 3-aminoisobutyric acid in human urine by enantioselective multidimensional capillary gas chromatography-mass spectrometry.

F Podebrad et al.

Clinica chimica acta; international journal of clinical chemistry, 292(1-2), 93-105 (2000-02-25)

The chiral metabolites 3-hydroxyisobutyric acid (HIBA) and 3-aminoisobutyric acid (AIBA) are intermediates in the pathways of L-valine and thymine and play an important role in the diagnosis of the very rare inherited metabolic diseases 3-hydroxyisobutyric aciduria (McKusick 236975) and methylmalonic

查看所有相关文献

全球贸易项目编号

货号	GTIN
16842-100MG	04061832404042