biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
MRQ-48, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (171M-94), vial of 0.5 mL concentrate (171M-95), bottle of 1.0 mL predilute (171M-97), vial of 1.0 mL concentrate (171M-96), bottle of 7.0 mL predilute (171M-98)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
isotype
IgG1
control
bone marrow
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic, membranous
General description
CD71, also known as the transferrin receptor, is a membrane glycoprotein that mediates the uptake of iron from transferrin for hemoglobin synthesis in erythroid cells. Early erythroid precursors and erythroblasts contain the highest mass of transferrin receptors, and expression is lost as these cells cease hemoglobin synthesis and mature into erythrocytes. Therefore, anti-CD71 is a useful marker for highlighting erythroid precursors in normal and neoplastic specimens.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
CD71 Positive Control Slides, Product No. 171S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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J Lesley et al.
Cellular immunology, 83(1), 14-25 (1984-01-01)
We have used a monoclonal antibody against the murine transferrin receptor to study the expression of the transferrin receptor on the hematopoietic progenitor cells (BFU-E, CFU-E, and CFU-C) present in mouse bone marrow. Elutriation and cell-sorting data are consistent with
C Sieff et al.
Blood, 60(3), 703-713 (1982-09-01)
Human bone marrow cells were separated on a fluorescence activated cell sorter (FACS) according to their binding of a series of monoclonal antibodies; the positive and negative fractions were cloned for erythroid burst and colony-forming units (BFU-E and CFU-E) and
P Ponka et al.
The international journal of biochemistry & cell biology, 31(10), 1111-1137 (1999-12-03)
The transferrin receptor is a membrane glycoprotein whose only clearly defined function is to mediate cellular uptake of iron from a plasma glycoprotein, transferrin. Iron uptake from transferrin involves the binding of transferrin to the transferrin receptor, internalization of transferrin
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 171M-96-RUO | 04061836539870 |
| 171M-97 | 0841683125426 |
| 171M-96 | 0841683125419 |
| 171M-98 | 0841683125433 |
| 171M-95 | 0841683125402 |
| 171M-94 | 0841683125396 |