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Merck
CN

17937

25-羟基维生素D2

≥95.0% (HPLC)

别名:

25-羟基维生素, 25-羟基麦角甾醇, 骨化二醇

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关于此项目

经验公式(希尔记法):
C28H44O2
化学文摘社编号:
分子量:
412.65
NACRES:
NA.28
PubChem Substance ID:
eCl@ss:
34058017
UNSPSC Code:
12352205
MDL number:
Beilstein/REAXYS Number:
4716773
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biological source

synthetic

Quality Level

assay

≥95.0% (HPLC)

form

crystalline powder

color

white

storage temp.

−20°C

SMILES string

[H][C@@]12CC[C@H]([C@H](C)\C=C\[C@H](C)C(C)(C)O)[C@@]1(C)CCC/C2=C\C=C3\C[C@@H](O)CCC3=C

InChI

1S/C28H44O2/c1-19-10-14-24(29)18-23(19)13-12-22-8-7-17-28(6)25(15-16-26(22)28)20(2)9-11-21(3)27(4,5)30/h9,11-13,20-21,24-26,29-30H,1,7-8,10,14-18H2,2-6H3/b11-9+,22-12+,23-13-/t20-,21+,24+,25-,26+,28-/m1/s1

InChI key

KJKIIUAXZGLUND-ICCVIKJNSA-N

Biochem/physiol Actions

麦角钙化醇(维生素D2)在 体内 通过羟基化反应而活化,生成25-羟基麦角钙化醇和1α,25-二羟基钙化醇。 活化的维生素D2分子可用于广泛的研究,以评估其对免疫功能和钙稳态等功能的影响。


pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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Paul Haggarty et al.
The British journal of nutrition, 109(5), 898-905 (2012-11-22)
The aims of the present study were to determine compliance with current advice on vitamin D and to assess the influence of season, dietary intake, supplement use and deprivation on vitamin D status in pregnant mothers and newborns in the
Kevin D Cashman et al.
The British journal of nutrition, 112(2), 193-202 (2014-05-02)
It has been suggested that vitamin D₂ is not very prevalent in the human food chain. However, data from a number of recent intervention studies suggest that the majority of subjects had measurable serum 25-hydroxyvitamin D₂ (25(OH)D₂) concentrations. Serum 25(OH)D₂
Anna-Maija Tolppanen et al.
Epidemiology (Cambridge, Mass.), 24(2), 310-319 (2013-02-05)
Higher serum total 25-hydroxyvitamin D (25(OH)D) concentrations have been associated with better lung function and lower risk of allergic disease. 25(OH)D3 constitutes the majority of total 25(OH)D and has been suggested to be more potent than 25(OH)D2. We studied the



全球贸易项目编号

货号GTIN
17937-1MG04061838754233