179M-9
CD79a (JCB117) Mouse Monoclonal Antibody
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
JCB117, monoclonal
Application:
immunohistochemistry (formalin-fixed, paraffin-embedded sections)
Species reactivity:
human
Citations:
10
Technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
JCB117, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (179M-94)
vial of 0.5 mL concentrate (179M-95)
bottle of 1.0 mL predilute (179M-97)
vial of 1.0 mL concentrate (179M-96)
bottle of 7.0 mL predilute (179M-98)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
isotype
IgG1κ
control
tonsil
shipped in
wet ice
storage temp.
2-8°C
visualization
membranous
Gene Information
human ... CD79A(973)
Analysis Note
 IVD |  IVD |  IVD |  RUO |
General description
Anti-CD79a is a B-cell marker that is generally used to complement CD20. This antibody will stain many of the same lymphomas as CD20, but also is more likely to stain precursor B-lymphoid leukemias than CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well. Anti-CD79a will stain many cases of acute promyelocytic leukemia (FAB-M3), but only rarely stains other types of myeloid leukemia.
Other Notes
CD79a Positive Control Slides, Product No. 179S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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此项目有
B T Lin et al.
Human pathology, 28(9), 1083-1090 (1997-10-06)
Primary plasmacytoma of the lymph nodes is very rare, and there are fewer than 20 reported cases. These cases appeared to have a better prognosis than other extramedullary plasmacytomas, with rare recurrence and no progression to myeloma after treatment. To
K Blakolmer et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 13(7), 766-772 (2000-07-27)
The monoclonal antibodies L26 (CD20) and CD79a are very useful reagents for the immunohistochemical assessment of B-cell lineage in lymphoproliferative disorders. Although very few CD20-positive peripheral T-cell lymphomas (PTL) have been reported, comprehensive analyses of CD79a reactivity in extranodal PTL
X Yao et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 14(2), 105-110 (2001-03-10)
Immunohistochemical studies are increasingly used for the routine diagnosis of lymphomas as it is widely accepted that lymphomas of different cell lineages vary in their prognosis and response to therapy. A case of peripheral T-cell lymphoma with aberrant expression of
Luis Requena et al.
Archives of dermatology, 139(4), 475-486 (2003-04-23)
Specific cutaneous involvement in patients with multiple myeloma (MM) is very uncommon. It usually occurs in late stages of MM as a reflection of increased tumor cell burden. We studied 8 patients with cutaneous involvement of MM without underlying bony
C J Van Noesel et al.
The Journal of experimental medicine, 175(6), 1511-1519 (1992-06-01)
We have recently reported that on human B lymphocytes, membrane IgM (mIgM) associates with a heterodimer of 47- and 37-kD polypeptides, the 47-kD subunit being encoded by the mb-1 gene. We show here that expression of mb-1, both at the
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