19899
CHAPS 100 mM 溶液
别名:
CHAPS 溶液
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关于此项目
经验公式（希尔记法）:
C32H58N2O7S
化学文摘社编号:
分子量:
614.88
MDL编号:
UNSPSC代码:
12161902
PubChem化学物质编号:
NACRES:
NA.25
描述
zwitterionic
表单
liquid
分子量
614.88 g/mol
浓度
100 mM in H2O
技术
protein quantification: suitable
CMC
8 mM
转变温度
cloud point >100 °C
密度
1.01 g/mL at 20 °C
储存温度
2-8°C
SMILES字符串
C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)CC4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
InChI
1S/C32H58N2O7S/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41)/t21-,22?,23-,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1
InChI key
UMCMPZBLKLEWAF-RFCNGIAKSA-N
一般描述
3-[（3-胆固醇氨丙基）二甲基氨基]-1-丙磺酸（CHAPS）是一种生物相容性表面活性剂。它是胆酸的衍生物，包含疏水的胆固醇样骨架，具有三个羟基和一个两性离子脂肪族尾。
应用
CHAPS 100 mM 溶液可用作裂解缓冲液的成分，用于提取山羊子宫内膜上皮细胞（EEC）和肝组织的蛋白质。
生化/生理作用
3-[（3-胆固醇氨丙基）二甲基氨基]-1-丙磺酸（CHAPS）具有硫代甜菜碱型表面活性剂和胆汁盐的特性。它参与蛋白质组学分析用蛋白质的提取过程，并使膜蛋白重建进入脂质囊泡内部（蛋白脂质体）。CHAPS被广泛应用于生物化学领域膜蛋白和受体的分离和纯化。由于其生物相容性、无电荷特性、非变性和非聚集特性，它可用于药物和医学领域。
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves
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