isotype
IgG
biological source
rabbit
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
SP107, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (200R-14), vial of 0.5 mL concentrate (200R-15), bottle of 1.0 mL predilute (200R-17), vial of 1.0 mL concentrate (200R-16), bottle of 7.0 mL predilute (200R-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
control
prostate
shipped in
wet ice
storage temp.
2-8°C
visualization
nuclear
General description
As a member of the steroid hormone superfamily, androgen receptor functions within distinctintracellular compartments to mediate cellular growth and transcriptional activation ofandrogen-regulated signaling pathways. Androgen receptor expression is broadly distributedacross a variety of normal tissue types. The anti-androgen receptor may be used as an aid toidentify carcinomas of the breast and prostate.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
Androgen Receptor Positive Control Slides, Product No. 200S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
A K Roy et al.
Annals of the New York Academy of Sciences, 949, 44-57 (2002-01-25)
Androgens are C-19 steroids secreted primarily from the testes and adrenals that play a critical role in reproduction. Reproductive functions of androgens are mediated through coordination of diverse physiological processes ranging from brain functions to specific cell proliferation and apoptosis.
Laura C Collins et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(7), 924-931 (2011-05-10)
Previous studies have demonstrated that androgen receptor is expressed in many breast cancers, but its expression in relation to the various breast cancer subtypes as defined by molecular profiling has not been studied in detail. We constructed tissue microarrays from
L O Gonzalez et al.
Histopathology, 50(7), 866-874 (2007-06-05)
To evaluate the expression of androgen receptors (AR) and two androgen-induced proteins [apolipoprotein D (ApoD) and pepsinogen C (PepC)] in ductal carcinoma in situ (DCIS) of the breast. AR, ApoD and PepC expression was examined in 28 cases of pure
Claire Bléchet et al.
Virchows Archiv : an international journal of pathology, 450(4), 433-439 (2007-03-03)
Previous studies have shown that C cells are twice as numerous in male than in female thyroids and that C cell hyperplasia (CCH) is much more frequent in men. These findings suggest regulation involving sex steroid hormones through the expression
R S Carroll et al.
Journal of neurosurgery, 82(3), 453-460 (1995-03-01)
The predominance of meningiomas in females, the accelerated growth of these tumors during the luteal phase of the menstrual cycle and during pregnancy, and the association between meningiomas and breast cancer have led to a number of studies examining the
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IHC antibodies enhance dermatopathology beyond H&E stained slides, improving techniques and applications for dermatological research.
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