21955
5(6)-羧基四甲基罗丹明N-琥珀酰亚胺酯
BioReagent, suitable for fluorescence, ≥70% (coupling to amines)
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关于此项目
经验公式（希尔记法）:
C29H25N3O7
化学文摘社编号:
分子量:
527.52
UNSPSC Code:
12352116
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
8739319
form
powder
InChI key
CXYYHBMOVJJZTD-UHFFFAOYSA-N
product line
BioReagent
assay
≥70% (coupling to amines)
InChI
1S/C29H25N3O7/c1-30(2)17-6-9-21-23(14-17)37-24-15-18(31(3)4)7-10-22(24)29(21)20-8-5-16(13-19(20)28(36)38-29)27(35)39-32-25(33)11-12-26(32)34/h5-10,13-15H,11-12H2,1-4H3
SMILES string
CN(C)c1ccc2c(Oc3cc(ccc3C24OC(=O)c5cc(ccc45)C(=O)ON6C(=O)CCC6=O)N(C)C)c1
solubility
DMF: soluble, acetonitrile: soluble, methanol: soluble
fluorescence
λex 543 nm; λem 576 nm in methanol, λex 554 nm; λem 584 nm in 0.1 M phosphate pH 8.0
suitability
suitable for fluorescence
storage temp.
−20°C
Quality Level
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Application
5（6）-羧四甲基罗丹明 N-琥珀酰亚胺酯（TMR-SE）可用作胺偶联剂，以形成5（6）-羧四甲基罗丹明（TMR）衍生的化合物，例如蛋白质和药物。
Packaging
无底玻璃瓶。内含物在插入的融合锥体内。
Other Notes
罗丹明衍生标签，可用于胺修饰和蛋白质缀合
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
L D Mayfield et al.
Bioorganic & medicinal chemistry letters, 9(10), 1419-1422 (1999-06-09)
Resins for solid-phase synthesis can affect coupling efficiencies by interacting with reactants. We have observed that polyethylene glycol-polystyrene (PEG-PS) solid support absorbs added activated fluorophores, preventing efficient labeling of peptide nucleic acids (PNAs). We now report that addition of an
E. Koller
Appl. Fluoresc. Technol., 3, 20-20 (1991)
Divyamani Srinivasan et al.
PloS one, 6(3), e17732-e17732 (2011-03-23)
Cell-penetrating peptides (CPPs) can transport macromolecular cargos into live cells. However, the cellular delivery efficiency of these reagents is often suboptimal because CPP-cargo conjugates typically remain trapped inside endosomes. Interestingly, irradiation of fluorescently labeled CPPs with light increases the release
P Kask et al.
Biophysical journal, 78(4), 1703-1713 (2000-03-29)
A method of sample analysis is presented which is based on fitting a joint distribution of photon count numbers. In experiments, fluorescence from a microscopic volume containing a fluctuating number of molecules is monitored by two detectors, using a confocal
Yoshiaki Yano et al.
Biochemistry, 41(9), 3073-3080 (2002-02-28)
Investigation of interactions between hydrophobic model peptides and lipid bilayers is perhaps the only way to elucidate the principles of the folding and stability of membrane proteins (White, S. H., and Wimley, W. C. (1998) Biochim. Biophys. Acta 1367, 339-352).
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