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经验公式(希尔记法):
C29H25N3O7
化学文摘社编号:
分子量:
527.52
UNSPSC Code:
12352116
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
8739319
产品名称
5(6)-羧基四甲基罗丹明N-琥珀酰亚胺酯, BioReagent, suitable for fluorescence, ≥70% (coupling to amines)
form
powder
InChI key
CXYYHBMOVJJZTD-UHFFFAOYSA-N
product line
BioReagent
assay
≥70% (coupling to amines)
InChI
1S/C29H25N3O7/c1-30(2)17-6-9-21-23(14-17)37-24-15-18(31(3)4)7-10-22(24)29(21)20-8-5-16(13-19(20)28(36)38-29)27(35)39-32-25(33)11-12-26(32)34/h5-10,13-15H,11-12H2,1-4H3
SMILES string
CN(C)c1ccc2c(Oc3cc(ccc3C24OC(=O)c5cc(ccc45)C(=O)ON6C(=O)CCC6=O)N(C)C)c1
solubility
DMF: soluble
acetonitrile: soluble
methanol: soluble
fluorescence
λex 543 nm; λem 576 nm in methanol
λex 554 nm; λem 584 nm in 0.1 M phosphate pH 8.0
suitability
suitable for fluorescence
storage temp.
−20°C
Quality Level
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Application
5(6)-羧四甲基罗丹明 N-琥珀酰亚胺酯(TMR-SE)可用作胺偶联剂,以形成5(6)-羧四甲基罗丹明(TMR)衍生的化合物,例如蛋白质和药物。
Other Notes
罗丹明衍生标签,可用于胺修饰和蛋白质缀合
Packaging
无底玻璃瓶。内含物在插入的融合锥体内。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
E. Koller
Appl. Fluoresc. Technol., 3, 20-20 (1991)
L D Mayfield et al.
Bioorganic & medicinal chemistry letters, 9(10), 1419-1422 (1999-06-09)
Resins for solid-phase synthesis can affect coupling efficiencies by interacting with reactants. We have observed that polyethylene glycol-polystyrene (PEG-PS) solid support absorbs added activated fluorophores, preventing efficient labeling of peptide nucleic acids (PNAs). We now report that addition of an
Divyamani Srinivasan et al.
PloS one, 6(3), e17732-e17732 (2011-03-23)
Cell-penetrating peptides (CPPs) can transport macromolecular cargos into live cells. However, the cellular delivery efficiency of these reagents is often suboptimal because CPP-cargo conjugates typically remain trapped inside endosomes. Interestingly, irradiation of fluorescently labeled CPPs with light increases the release
P Kask et al.
Biophysical journal, 78(4), 1703-1713 (2000-03-29)
A method of sample analysis is presented which is based on fitting a joint distribution of photon count numbers. In experiments, fluorescence from a microscopic volume containing a fluctuating number of molecules is monitored by two detectors, using a confocal
Angela María Barbero et al.
Journal of leukocyte biology, 109(1), 257-273 (2020-09-30)
Tuberculosis dates back to ancient times but it is not a problem of the past. Each year, millions of people die from tuberculosis. After inhalation of infectious droplet nuclei, Mycobacterium tuberculosis reaches the lungs where it can manipulate the immune
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