biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
CALP, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (231M-14)
vial of 0.5 mL concentrate (231M-15)
bottle of 1.0 mL predilute (231M-17)
vial of 1.0 mL concentrate (231M-16)
bottle of 7.0 mL predilute (231M-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
isotype
IgG1κ
control
appendix
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Analysis Note
 IVD |  IVD |  IVD |  RUO |
General description
Calponin is a 34 kD polypeptide that interacts with actin, tropomyosin, and calmodulin. It is involved in smooth muscle contraction mechanism and is restricted exclusively to smooth muscle tissue. Anti-calponin has been found to be useful in differentiating benign sclerosing lesions of the breast from carcinoma. Calponin positivity has also been noted in malignant myoepithelioma and pleomorphic adenoma of salivary gland origin, as well as angiomatoid malignant fibrous histiocytoma.
Other Notes
Calponin Positive Control Slides, Product No. 231S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
Antibodies to novel myoepithelium-associated proteins distinguish be-nign lesions and carcinoma in situ from invasive carcinoma of the breast
Wang NP, Wan BC, et al.
Appl. Immunohistochem., 5(3), 141-151 (1997)
J C Fanburg-Smith et al.
Human pathology, 30(11), 1336-1343 (1999-11-26)
Angiomatoid "malignant" fibrous histiocytoma (AMFH) has been considered to be a low-grade sarcoma of childhood, and, with its fibrous pseudocapsule, angiomatoid change, dense lymphoplasmacytic response, and proliferation of spindled or round cells, has been classified as a fibrohistiocytic neoplasm. We
A T Savera et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 10(11), 1093-1100 (1997-12-05)
Myoepithelial cells of salivary glands have a complex cytoskeletal immunophenotype. To elaborate the smooth muscle phenotype of salivary gland myoepithelium and to assess its contribution to the histogenesis of pleomorphic adenomas, we evaluated the immunohistochemical expression of three novel monoclonal
T Nagao et al.
Cancer, 83(7), 1292-1299 (1998-10-08)
Malignant myoepithelioma (MME) of the salivary gland, also known as myoepithelial carcinoma, is rare and its biologic behavior has not been clarified fully. Ten cases of MME were analyzed for their clinicopathologic features and immunohistochemical characteristics, focusing on prognostic factors
Jason L Hornick et al.
The American journal of surgical pathology, 27(9), 1183-1196 (2003-09-10)
Myoepitheliomas and mixed tumors were only recently recognized to occur primarily in soft tissue, and only small case numbers have been described. To characterize these tumors further and to evaluate prognostic parameters, 101 myoepithelial tumors of soft tissue were retrieved
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