跳转至内容
Merck
CN

244R-1

DOG1 (SP31) Rabbit Monoclonal Antibody

登录 查看组织和合同定价。

选择尺寸

关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
SP31, monoclonal
Application:
IHC (p)
Citations:
4

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

biological source

rabbit

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

SP31, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (244R-14), vial of 0.5 mL concentrate (244R-15), bottle of 1.0 mL predilute (244R-17), vial of 1.0 mL concentrate (244R-16), bottle of 7.0 mL predilute (244R-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG

control

GIST

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic, membranous

Quality Level

100, 500

Gene Information

human ... ANO1(55107)

相关类别

General description

DOG1 is a calcium-dependent chloride channel protein that is encoded by a gene called TMEM16A (TMEM16 FLJ10261, ANO1, ORAOV2, and AOS2) located on chromosome 11q13. DOG1 has many significant functions such as regulation of the cholinergic activity of gastrointestinal smooth muscle and regulation of both the survival and proliferation of cells. Anti-DOG1 antibody has been shown to be useful in the identification of gastrointestinal stromal tumors (GIST).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD
IVD
IVD
RUO

Other Notes

DOG1 Positive Control Slides, Product No. 244S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

未找到合适的产品？  

试试我们的产品选型工具.

存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000482028
0000482028
0000477598
0000477597
0000477597

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

J R Parfitt et al.
Histopathology, 52(7), 816-823 (2008-05-23)
Gastrointestinal Kaposi's sarcoma (KS) may mimic gastrointestinal stromal tumours (GISTs) histologically. Studies have shown that KS outside the gastrointestinal (GI) tract may express CD117, an antibody usually used to support a diagnosis of GIST. The aim was to evaluate the
Inigo Espinosa et al.
The American journal of surgical pathology, 32(2), 210-218 (2008-01-29)
Gastrointestinal stromal tumors (GIST) occur primarily in the wall of the intestine and are characterized by activating mutations in the receptor tyrosine kinases genes KIT or PDGFRA. The diagnosis of GIST relies heavily on the demonstration of KIT/CD117 protein expression
Robert B West et al.
The American journal of pathology, 165(1), 107-113 (2004-06-25)
We recently characterized gene expression patterns in gastrointestinal stromal tumors (GISTs) using cDNA microarrays, and found that the gene FLJ10261 (DOG1, discovered on GIST-1), encoding a hypothetical protein, was specifically expressed in GISTs. The immunoreactivity of a rabbit antiserum to
Shigeharu Miwa et al.
Journal of gastroenterology, 43(7), 531-537 (2008-07-24)
Recently, the novel gene DOG1 has been found to be overexpressed in most gastrointestinal stromal tumors (GISTs) specifically within the field of soft tissue tumors. DOG1 might play a role in development of GISTs and have potential as a diagnostic

商品

Immunohistochemistry Applications in Gastrointestinal Cancer

Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.

胃肠道癌症中的免疫组织化学应用

结直肠癌是男性和女性中第三大常见癌症。预计2016年将发生136,000例结直肠癌。

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持