biological source
rabbit
conjugate
unconjugated
antibody form
Ig fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (250A-14)
vial of 0.5 mL concentrate (250A-15)
bottle of 1.0 mL predilute (250A-17)
vial of 1.0 mL concentrate (250A-16)
bottle of 7.0 mL predilute (250A-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10-1:50
control
placenta
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... VWF(7450)
Analysis Note
 IVD |  IVD |  IVD |  RUO |
General description
Factor VIII-Related Antigen or von Willebrand factor is a glycoprotein associated with hemostasis in promoting the adhesion of platelets. Anti-Factor VIII Related Antigen reactivity is seen in endothelial cells, hemangioma, and the majority of tumors of endothelial origin such as Kaposi’s sarcoma and angiosarcoma.
Other Notes
Factor VIII-R Ag. (polyclonal) Positive Control Slides, Product No. 250S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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U K Zätterström et al.
Head & neck, 17(4), 312-318 (1995-07-01)
The progression of tumor growth requires the recruitment of new blood vessels. It has been suggested that the degree of neovascularization would correlate with clinical prognosis. The purpose of the present study was to ascertain whether tumor vascularization correlated with
J Bhawan et al.
Cancer, 55(3), 570-576 (1985-02-01)
A patient was diagnosed as having angioendotheliomatosis proliferans systemisata (APS) based on characteristic clinical and histologic features. A few days later, malignant lymphoma involving the gut was discovered. Immunohistochemical and electronmicroscopic studies confirmed the nonendothelial and lymphoid nature of intravascular
J Ansell et al.
Cancer, 50(8), 1506-1512 (1982-10-15)
The case history of a patient with diffuse histiocytic lymphoma and skin lesions characteristic of malignant angioendotheliomatosis is reported. The patient initially responded to aggressive chemotherapy but quickly had a relapse, CNS disease developed, and the patient died one year
X W Bian et al.
Analytical and quantitative cytology and histology, 22(3), 267-274 (2000-06-29)
To investigate the correlation of angiogenic factor expression levels with the degrees of malignancy and vascularity and their clinicopathologic significance in astrocytomas. Factor VIII-related antigen (FVIII-RAg) was used as the marker of endothelia and basic fibroblast growth factor (bFGF); FGF
K H Fulling et al.
Cancer, 51(6), 1107-1118 (1983-03-15)
Two cases of neoplastic angioendotheliomatosis are described. Both patients presented with subacute development of dementia punctuated by focal neurologic signs. Postmortem examination in both cases disclosed a vasculocentric distribution of neoplastic cells in many organs. Two characteristic histologic patterns were
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