biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
23A3, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (257M-14), vial of 0.5 mL concentrate (257M-15), bottle of 1.0 mL predilute (257M-17), vial of 1.0 mL concentrate (257M-16), bottle of 7.0 mL predilute (257M-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
isotype
IgG2a
control
breast, breast carcinoma
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... PIP(5304)
General description
GCDFP-15 is a 15 kD glycoprotein which is localized in the apocrine metaplastic epithelium lining breast cysts and in apocrine glands in the axilla, vulva, eyelid, ear canal, and in salivary glands. Approximately 70% of breast carcinomas are labeled with antibody to GCDFP-15. Colorectal carcinomas, lung carcinoma, mesothelimas rarely stain with this antibody. Because of its specificity for breast carcinoma (up to 99%), this antibody is often used in a screening panel in the appropriate clinical situation, often for a woman with metastasis of unknown primary.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
GCDFP-15 Positive Control Slides, Product No. 257S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
法规信息
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商品
免疫组织化学（免疫组化，IHC）用于表征所有组织中的细胞内蛋白质或各种细胞表面。个体标记，或更常用的各种标记蛋白质组，可用于表征各种肿瘤亚型，确定原发组织，区分转移性肿瘤和原发性肿瘤，并提供可能对预后有重要意义、预测对治疗的响应、或评估残留肿瘤后处理的其他信息。
P Viacava et al.
Virchows Archiv : an international journal of pathology, 432(3), 255-260 (1998-04-09)
GCDFP-15, a glycoprotein identified in the cyst fluid of cystic breast disease, is considered to be a marker of apocrine differentiation. Studies on GCDFP-15 localization in adult normal tissues are lacking, and no information on GCDFP-15 expression during fetal development
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 227-228 (2014)
A H Ormsby et al.
Journal of the American Academy of Dermatology, 32(5 Pt 1), 711-716 (1995-05-01)
For accurate classification of cutaneous metastatic carcinoma, reliable tumor-specific immunohistochemical markers would be valuable. Our purpose was to analyze the sensitivity, specificity, and positive predictive value of gross cystic disease fluid protein-15 (GCDFP-15) and estrogen receptor protein (ERP) for diagnosing
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 257M-14 | 0841683130796 |
| 257M-15 | 0841683130802 |
| 257M-18 | 0841683130833 |
| 257M-17 | 0841683130826 |
| 257M-16-RUO | 04061836529734 |
| 257M-16 | 0841683130819 |