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Merck
CN

262R-1

Sigma-Aldrich

Granzyme B (EP230) Rabbit Monoclonal Primary Antibody

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关于此项目

UNSPSC代码:
12352203
NACRES:
NA.41
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生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

EP230, monoclonal

描述

(For In Vitro Diagnostic Use in Select Regions (See Chart))

表单

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (262R-14)
vial of 0.5 mL concentrate (262R-15)
bottle of 1.0 mL predilute (262R-17)
vial of 1.0 mL concentrate (262R-16)
bottle of 7.0 mL predilute (262R-18)

制造商/商品名称

Cell Marque®

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同位素/亚型

IgG

控制

anaplastic large cell lymphoma, spleen

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic

基因信息

human ... GZMB(3002)

一般描述

Granzymes are serine proteases which are stored in specialized lytic granules of cytotoxic T-lymphocytes and in natural killer cells.1 Anti-granzyme B has been useful in in the identification of natural killer/T-cell lymphoma, as well as anaplastic large cell lymphoma.2-4

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

分析说明


IVD

IVD

IVD

RUO

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Granzyme B Positive Control Slides, Product No. 262S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

法律信息

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J J Oudejans et al.
The American journal of pathology, 148(1), 233-240 (1996-01-01)
Reed-Sternberg (RS) and Hodgkin's (H) cells are considered to be the neoplastic cells in Hodgkin's disease. Although most data suggest a lymphoid origin, the nature of these cells still remains the subject of considerable controversy. Recently, monoclonal antibodies became available
J A Kummer et al.
Clinical and experimental immunology, 100(1), 164-172 (1995-04-01)
Cytoplasmic granules from activated natural killer (NK) and cytotoxic T lymphocytes (CTL) contain a pore-forming protein, perforin, and several homologous serine proteinases called granzymes. Expression of these proteins correlates with the cytolytic potential of cytotoxic lymphocytes. Using a panel of
Naoko Kato et al.
The American Journal of dermatopathology, 25(2), 142-147 (2003-03-26)
A neutrophil-rich anaplastic large cell lymphoma (ALCL) presented in the skin of a 47-year-old Japanese woman. The solitary cutaneous lesion was an eroded, 10-mm, dome-shaped nodule involving the skin of her left upper arm. Histologically, it showed a proliferation of
Jie Liu et al.
The Journal of dermatology, 30(10), 735-741 (2003-12-20)
Nasal natural killer (NK)/T cell lymphoma is an Epstein-Barr virus (EBV) associated lymphoma that arises in the nasal area and aggressively invades surrounding tissues. Our patient was a 48-year-old male who had had nasal obstruction and nasal discharge for 2
Brett E Johnson et al.
Cell reports. Medicine, 3(2), 100525-100525 (2022-03-05)
Mechanisms of therapeutic resistance and vulnerability evolve in metastatic cancers as tumor cells and extrinsic microenvironmental influences change during treatment. To support the development of methods for identifying these mechanisms in individual people, here we present an omic and multidimensional

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