26420
Chloro(2,2′:6′,2″-terpyridine)platinum(II) chloride dihydrate
≥99.0% (AAS)
别名:
Dichloro(2,2′:6′,2′′-terpyridine)platinum(II) dihydrate
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关于此项目
经验公式（希尔记法）:
C15H11Cl2N3Pt · 2H2O
化学文摘社编号:
分子量:
535.28
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
InChI
1S/C15H11N3.2ClH.2H2O.Pt/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13;;;;;/h1-11H;2*1H;2*1H2;/q;;;;;+2/p-2
SMILES string
O.O.Cl[Pt]Cl.c1ccc(nc1)-c2cccc(n2)-c3ccccn3
InChI key
WEBUYGBVKZYTMT-UHFFFAOYSA-L
assay
≥99.0% (AAS)
Quality Level
Other Notes
An intercalator of helical and double stranded DNA; Spectroscopic tag for proteins. Selective covalent labeling of histidine in cytochromes c; Intercalation
wgk
WGK 3
flash_point_f
Not applicable
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
K W Jennette et al.
Proceedings of the National Academy of Sciences of the United States of America, 71(10), 3839-3843 (1974-10-01)
The red, cationic complex 2-hydroxy-ethanethiolato(2,2',2''-terpyridine)platinum(II), [(terpy)-Pt(SCH(2)CH(2)OH)](+), binds strongly to DNA by a mechanism involving intercalation. By means of fluorescence spectroscopy, the platinum complex was shown to inhibit competitively the binding of the intercalating dye ethidium bromide to calf thymus DNA.
E.M.A. Ratilla et al.
Journal of the American Chemical Society, 109, 4592-4592 (1987)
S. J. Lippard
Accounts of Chemical Research, 11, 211-211 (1987)
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