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Merck
CN

264M-9

Hepatocyte Specific Antigen (Hep Par-1) (OCH1E5) Mouse Monoclonal Antibody

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
OCH1E5, monoclonal
Application:
immunohistochemistry (formalin-fixed, paraffin-embedded sections)
Species reactivity:
human
Citations:
6
Technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
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biological source

mouse

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

OCH1E5, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (264M-94)
vial of 0.5 mL concentrate (264M-95)
bottle of 1.0 mL predilute (264M-97)
vial of 1.0 mL concentrate (264M-96)
bottle of 7.0 mL predilute (264M-98)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG1κ

control

liver

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Quality Level

Analysis Note


IVD

IVD

IVD

RUO

General description

Anti-hepatocyte specific antigen, also known as anti-Hep-Par1 (hepatocyte paraffin 1),recognizes both benign and malignant liver-derived tissues including such tumors ashepatocellular carcinoma. It recognizes both normal adult and fetal liver tissue. The typicalpattern is granular cytoplasmic staining. This antibody is useful in identifying hepatocellularcarcinomas.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Hepatocyte Specific Antigen (Hep-Par1)(OCH1E5) Positive Control Slides, Product No. 264S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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分析证书(COA)

Lot/Batch Number

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W M Tsui et al.
The American journal of surgical pathology, 23(1), 34-48 (1999-01-15)
Hepatic angiomyolipoma (AML) is frequently misdiagnosed. HMB-45 is a promising immunomarker for this tumor that leads to recognition of some AMLs with unusual morphology. The purpose of this collaborative study is to better define the morphologic variations of AML. Thirty
M Fasano et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 11(10), 934-938 (1998-10-31)
The distinction of hepatoblastoma, especially the embryonal type, from other small, round-cell tumors of childhood can sometimes be difficult. Polyclonal anticarcinoembryonic antigen (pCEA) and Hepatocyte Paraffin 1 (Hep Par 1) are immunohistochemical markers that are useful in the diagnosis of
M I Minervini et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 10(7), 686-692 (1997-07-01)
A monoclonal antibody highly specific for benign and malignant hepatocytes (HepPar 1) was evaluated as part of an antibody panel used to differentiate hepatocellular from nonhepatocellular neoplasms. Sixty-five liver tumors and two extrahepatic tumors from patients with documented liver tumors
A Maitra et al.
American journal of clinical pathology, 115(5), 689-694 (2001-05-11)
Hepatocyte paraffin 1 (Hep Par 1) is a monoclonal antibody considered almost specific for normal and neoplastic hepatocytes, that can be used on formalin-fixed paraffin-embedded tissues. Hep Par 1 reactivity has been demonstrated consistently in hepatocellular carcinomas and hepatoblastomas but
Tad J Wieczorek et al.
American journal of clinical pathology, 118(6), 911-921 (2002-12-11)
We compared the effectiveness of thyroid transcription factor-1 (TTF-1, cytoplasmic reactivity) and hepatocyte antigen (HPA) as markers for characterization of hepatocellular carcinoma (HCC) and as discriminators to distinguish HCC from its histologic and cytologic mimics. Formalin-fixed, paraffin-embedded sections of 258

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