264R-1
Hepatocyte Specific Antigen (Hep-Par1) (EP265) Rabbit Monoclonal Primary Antibody
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
EP265, monoclonal
Application:
immunohistochemistry (formalin-fixed, paraffin-embedded sections)
Species reactivity:
human
Citations:
5
Technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
biological source
rabbit
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
EP265, monoclonal
description
(For In Vitro Diagnostic Use in Select Regions (See Chart))
form
buffered aqueous solution
species reactivity
human
packaging
bottle of 1.0 mL predilute (264R-17)
bottle of 7.0 mL predilute (264R-18)
vial of 0.1 mL concentrate (264R-14)
vial of 0.5 mL concentrate (264R-15)
vial of 1.0 mL concentrate (264R-16)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
isotype
IgG
shipped in
wet ice
storage temp.
2-8°C
Analysis Note
 IVD |  IVD |  IVD |  RUO |
General description
Anti-hepatocyte specific antigen, also known as anti-Hep-Par1, recognizes both benign and malignant liver-derived tissues including such tumors as hepatoblastoma, hepatocellular carcinoma, and hepatic adenoma. It recognizes both normal adult and fetal liver tissue. The typical pattern is a granular cytoplasmic staining. This antibody is useful in differentiating hepatocellular carcinomas with adenoid features from adenocarcinomas, either primary in the liver or metastatic lesions to the liver.1-3 In labeling hepatoblastoma, it is useful in differentiating this entity from other small round cell tumors.4,5
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Hepatocyte Specific Antigen (Hep-Par1)(OCH1E5) Positive Control Slides, Product No. 264S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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此项目有
M I Minervini et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 10(7), 686-692 (1997-07-01)
A monoclonal antibody highly specific for benign and malignant hepatocytes (HepPar 1) was evaluated as part of an antibody panel used to differentiate hepatocellular from nonhepatocellular neoplasms. Sixty-five liver tumors and two extrahepatic tumors from patients with documented liver tumors
A Maitra et al.
American journal of clinical pathology, 115(5), 689-694 (2001-05-11)
Hepatocyte paraffin 1 (Hep Par 1) is a monoclonal antibody considered almost specific for normal and neoplastic hepatocytes, that can be used on formalin-fixed paraffin-embedded tissues. Hep Par 1 reactivity has been demonstrated consistently in hepatocellular carcinomas and hepatoblastomas but
Tad J Wieczorek et al.
American journal of clinical pathology, 118(6), 911-921 (2002-12-11)
We compared the effectiveness of thyroid transcription factor-1 (TTF-1, cytoplasmic reactivity) and hepatocyte antigen (HPA) as markers for characterization of hepatocellular carcinoma (HCC) and as discriminators to distinguish HCC from its histologic and cytologic mimics. Formalin-fixed, paraffin-embedded sections of 258
M Fasano et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 11(10), 934-938 (1998-10-31)
The distinction of hepatoblastoma, especially the embryonal type, from other small, round-cell tumors of childhood can sometimes be difficult. Polyclonal anticarcinoembryonic antigen (pCEA) and Hepatocyte Paraffin 1 (Hep Par 1) are immunohistochemical markers that are useful in the diagnosis of
Peiguo G Chu et al.
The American journal of surgical pathology, 26(8), 978-988 (2002-08-10)
Hepatocyte monoclonal antibody (Hep) (alternatively Hep Par 1 for Hep paraffin 1) has been reported to stain normal hepatic tissue and hepatocellular carcinoma (HCC) with high specificity. We have studied the Hepatocyte expression in 96 cases of HCC and 311
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