biological source
rabbit
conjugate
unconjugated
antibody form
Ig fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (268A-14)
vial of 0.5 mL concentrate (268A-15)
bottle of 1.0 mL predilute (268A-17)
vial of 1.0 mL concentrate (268A-16)
bottle of 7.0 mL predilute (268A-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
control
tonsil
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Analysis Note
![]() IVD | ![]() IVD | ![]() IVD | ![]() RUO |
General description
Anti-IgD antibody reacts with surface immunoglobulin IgD delta chains. This antibody is useful when identifying leukemias, plasmacytomas, and B-cell lineage derived lymphomas (in particular Marginal Zone Lymphoma). Cytoplasmic staining is easily identified on paraffin tissue. Surface immunoglobulin is difficult to demonstrate on paraffin sections but can be demonstrated on frozen sections.
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
IgD (polyclonal) Positive Control Slides, Product No. 268S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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M Mollejo et al.
The American journal of surgical pathology, 21(7), 772-780 (1997-07-01)
Splenic marginal zone lymphoma (SMZL) has recently been proposed as a distinctive type of low-grade B-cell lymphoma. Although there is general agreement that this entity exists, its precise definition is blurred by uncertainty in differential diagnosis from other low-grade B-cell
M Bertero et al.
Journal of the American Academy of Dermatology, 30(1), 23-30 (1994-01-01)
Mantle zone lymphoma (MZL) is a B-cell proliferation regarded as the follicular variant of intermediate lymphocytic lymphoma (ILL). Neoplastic small lymphoid cells proliferate as wide mantles around atrophic centers of benign appearance. The clinical, histologic, and immunohistochemical features of four
E Campo et al.
The American journal of surgical pathology, 23(1), 59-68 (1999-01-15)
The existence of primary nodal marginal zone lymphomas (MZL) is controversial, as is their relationship to putative extranodal counterparts. Most nodal lymphomas with monocytoid B cell/marginal zone differentiation exhibit the morphologic and immunophenotypical characteristics of extranodal MALT-lymphomas. Splenic marginal zone
I Anagnostopoulos et al.
Histopathology, 39(6), 561-565 (2002-03-21)
We report a case of mantle cell lymphoma masquerading as a marginal zone cell lymphoma. In the initial manifestation in the palatine tonsils, the neoplastic cells were found to grow exclusively within the marginal zones of secondary follicles which showed
S Mori et al.
Acta pathologica japonica, 36(10), 1429-1440 (1986-10-01)
Expression of IgD was studied immunopathologically on 50 cases of B cell lymphomas (B MLs), together with various B cell markers including IgM, kappa and lambda chains, B1, B2, (OK)B2, (OB)B7, (OK)T10, NUB1, Leu 1, Leu 14, and PCA. IgD
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