biological source
rabbit
conjugate
unconjugated
antibody form
Ig fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (268A-14)
vial of 0.5 mL concentrate (268A-15)
bottle of 1.0 mL predilute (268A-17)
vial of 1.0 mL concentrate (268A-16)
bottle of 7.0 mL predilute (268A-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
control
tonsil
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Analysis Note
 IVD |  IVD |  IVD |  RUO |
General description
Anti-IgD antibody reacts with surface immunoglobulin IgD delta chains. This antibody is useful when identifying leukemias, plasmacytomas, and B-cell lineage derived lymphomas (in particular Marginal Zone Lymphoma). Cytoplasmic staining is easily identified on paraffin tissue. Surface immunoglobulin is difficult to demonstrate on paraffin sections but can be demonstrated on frozen sections.
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
IgD (polyclonal) Positive Control Slides, Product No. 268S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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M Mollejo et al.
The American journal of surgical pathology, 21(7), 772-780 (1997-07-01)
Splenic marginal zone lymphoma (SMZL) has recently been proposed as a distinctive type of low-grade B-cell lymphoma. Although there is general agreement that this entity exists, its precise definition is blurred by uncertainty in differential diagnosis from other low-grade B-cell
M Bertero et al.
Journal of the American Academy of Dermatology, 30(1), 23-30 (1994-01-01)
Mantle zone lymphoma (MZL) is a B-cell proliferation regarded as the follicular variant of intermediate lymphocytic lymphoma (ILL). Neoplastic small lymphoid cells proliferate as wide mantles around atrophic centers of benign appearance. The clinical, histologic, and immunohistochemical features of four
K Oka et al.
Acta haematologica, 90(2), 84-89 (1993-01-01)
Biopsy specimens obtained from 2 patients with monocytoid B cell lymphoma, 7 with mantle zone lymphoma, 7 with small lymphocytic lymphoma or B chronic lymphocytic leukemia, and 6 with hairy cell leukemia were investigated using an immunohistochemical method to detect
D Gupta et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 13(11), 1161-1166 (2000-12-06)
Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) typically involves nodal or extranodal tissues as a diffuse proliferation with pseudofollicular growth centers obliterating normal architecture. We describe 16 cases of CLL/SLL in which the neoplasm was confined to the marginal zone, perifollicular
E Campo et al.
The American journal of surgical pathology, 23(1), 59-68 (1999-01-15)
The existence of primary nodal marginal zone lymphomas (MZL) is controversial, as is their relationship to putative extranodal counterparts. Most nodal lymphomas with monocytoid B cell/marginal zone differentiation exhibit the morphologic and immunophenotypical characteristics of extranodal MALT-lymphomas. Splenic marginal zone
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