271R-2
Inhibin, alpha (MRQ-63) Rabbit Monoclonal Antibody
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关于此项目
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
MRQ-63, monoclonal
Application:
immunohistochemistry (formalin-fixed, paraffin-embedded sections)
Species reactivity:
human
Citations:
9
Technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
biological source
rabbit
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
MRQ-63, monoclonal
description
For In Vitro Diagnostic Use in Select Regions
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (271R-24)
vial of 0.1 mL concentrate Research Use Only (271R-24-RUO)
vial of 0.5 mL concentrate (271R-25)
vial of 1.0 mL concentrate (271R-26)
vial of 1.0 mL concentrate Research Use Only (271R-26-RUO)
vial of 1.0 mL pre-dilute Research Use Only (271R-27-RUO)
vial of 1.0 mL pre-dilute ready-to-use (271R-27)
vial of 7.0 mL pre-dilute ready-to-use (271R-28)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (271R-28-RUO)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
isotype
IgG
control
adrenal cortex
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... INHA(3623)
Analysis Note
 IVD |  IVD |  IVD |  RUO |
General description
Inhibin is a peptide hormone that inhibits FSH secretion from the pituitary. Inhibin is a dimer that consists of an alpha and beta subunit. In normal tissue, anti-inhibin alpha labels granulosa cells of the ovary, sertoli and Leydig cells of the testis, and the zona reticularis of the adrenal cortex. Anti-inhibin alpha has demonstrated utility in the identification of sex cord-stromal tumors and adrenal cortical tumors.
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Inhibin, alpha Positive Control Slides, Product No. 271S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
Preparation Note
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Note: This IFU may not apply to your specific product lot.
Note: This requires a keycode which can be found on your packaging or product label.
Download the latest released IFU
Note: This IFU may not apply to your specific product lot.
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
W G McCluggage et al.
Journal of clinical pathology, 51(2), 114-116 (1998-05-29)
To investigate the immunohisto-chemical staining of normal, hyperplastic, and neoplastic adrenal cortex with a monoclonal antibody against alpha inhibin. Also, to determine whether immunostaining with this antibody is useful in differentiating between adrenal cortical neoplasms and other tumours involving the
K Yamashita et al.
American journal of obstetrics and gynecology, 177(6), 1450-1457 (1998-01-10)
Our purpose was to examine the cellular localization of inhibin subunits and messenger ribonucleic acid expressions for the inhibin subunits and the serum levels of inhibin A and inhibin B in human ovarian sex cord stromal tumors. We examined the
F Kommoss et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 11(7), 656-664 (1998-08-04)
We investigated 203 ovarian tumors and tumor-like lesions for inhibin expression using a monoclonal anti-inhibin alpha antibody. Inhibin was present in the tumor cells in all 14 primary adult granulosa cell tumors (4 luteinized) plus 3 metastatic, all 10 primary
K A Iczkowski et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 11(8), 774-779 (1998-08-28)
We compared the expression of inhibin A, chromogranin, synaptophysin, S-100 protein, cytokeratins AE1/AE3, 7, and 20, and estrogen and progesterone receptors in testicular sex cord-stromal tumors: 11 Sertoli cell tumors, 3 Sertoli cell adenomas (nodules), 26 benign Leydig cell tumors
L M Munro et al.
The Journal of endocrinology, 161(2), 341-347 (1999-05-13)
Inhibins and activins are dimeric proteins of the transforming growth factor-beta superfamily which have been shown to be expressed in the adrenal cortex. Recent studies have suggested a role for these peptides in the pathogenesis and/or function of adrenal tumours.
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