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Merck
CN

271R-2

Sigma-Aldrich

Inhibin, alpha (MRQ-63) Rabbit Monoclonal Antibody

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UNSPSC代码:
12352203

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生物来源

rabbit

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

MRQ-63, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions

表单

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (271R-24)
vial of 0.1 mL concentrate Research Use Only (271R-24-RUO)
vial of 0.5 mL concentrate (271R-25)
vial of 1.0 mL concentrate (271R-26)
vial of 1.0 mL concentrate Research Use Only (271R-26-RUO)
vial of 1.0 mL pre-dilute Research Use Only (271R-27-RUO)
vial of 1.0 mL pre-dilute ready-to-use (271R-27)
vial of 7.0 mL pre-dilute ready-to-use (271R-28)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (271R-28-RUO)

制造商/商品名称

Cell Marque®

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)

同位素/亚型

IgG

控制

adrenal cortex

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic

基因信息

human ... INHA(3623)

相关类别

一般描述

Inhibin is a peptide hormone that inhibits FSH secretion from the pituitary. Inhibin is a dimer that consists of an alpha and beta subunit. In normal tissue, anti-inhibin alpha labels granulosa cells of the ovary, sertoli and Leydig cells of the testis, and the zona reticularis of the adrenal cortex. Anti-inhibin alpha has demonstrated utility in the identification of sex cord-stromal tumors and adrenal cortical tumors.

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

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分析说明


IVD
IVD
IVD
RUO

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Inhibin, alpha Positive Control Slides, Product No. 271S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

法律信息

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000450656
0000450677
0000450677
0000450656
0000448117

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W G McCluggage et al.
Journal of clinical pathology, 51(2), 114-116 (1998-05-29)
To investigate the immunohisto-chemical staining of normal, hyperplastic, and neoplastic adrenal cortex with a monoclonal antibody against alpha inhibin. Also, to determine whether immunostaining with this antibody is useful in differentiating between adrenal cortical neoplasms and other tumours involving the
C Guerrieri et al.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 17(3), 266-271 (1998-07-10)
We have investigated the use of inhibin and cytokeratin-7 (CK-7) in distinguishing endometrioid ovarian carcinomas (both typical and sex cord-like) form granulosa cell and Sertoli cell-containing ovarian tumors. Immunohistochemical staining with inhibin, CK-7, and epithelial membrane antigen (EMA) was performed
C J Stewart et al.
Histopathology, 31(1), 67-74 (1997-07-01)
Inhibin is a heterodimeric protein hormone which appears to be a sensitive serological and immunohistochemical marker of ovarian granulosa cell tumours. The purposes of this study were to examine inhibin immunoreactivity in a wide range of gonadal stromal neoplasms and
W G McCluggage
Journal of clinical pathology, 53(5), 327-334 (2000-07-13)
This leader reviews recent advances in immunohistochemistry that are useful in the diagnosis of ovarian neoplasms. These include the value of different anticytokeratin antibodies in the distinction between a primary ovarian adenocarcinoma and a metastatic adenocarcinoma, especially of colorectal origin.
L M Munro et al.
The Journal of endocrinology, 161(2), 341-347 (1999-05-13)
Inhibins and activins are dimeric proteins of the transforming growth factor-beta superfamily which have been shown to be expressed in the adrenal cortex. Recent studies have suggested a role for these peptides in the pathogenesis and/or function of adrenal tumours.
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