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275R-3

Ki-67 (MRQ-64) Rabbit Monoclonal Antibody

Name: Ki-67 (MRQ-64) Rabbit Monoclonal Antibody
Brand: SIGMA

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关于此项目

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

MRQ-64, monoclonal

Application:

IHC (p)

Citations:

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属性

biological source

rabbit

Quality Segment

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

MRQ-64, monoclonal

description

For In Vitro Diagnostic Use in Select Regions

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (275R-34), vial of 0.1 mL concentrate Research Use Only (275R-34-RUO), vial of 0.5 mL concentrate (275R-35), vial of 1.0 mL concentrate (275R-36), vial of 1.0 mL concentrate Research Use Only (275R-36-RUO), vial of 1.0 mL pre-dilute Research Use Only (275R-37-RUO), vial of 1.0 mL pre-dilute ready-to-use (275R-37), vial of 25.0 mL pre-dilute ready-to-use (275R-30), vial of 25.0 mL pre-dilute ready-to-use Research Use Only (275R-30-RUO), vial of 7.0 mL pre-dilute ready-to-use (275R-38), vial of 7.0 mL pre-dilute ready-to-use Research Use Only (275R-38-RUO)

manufacturer/tradename

Cell Marque^®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)

isotype

IgG

control

Burkitt lymphoma, breast (ductl carcinoma in situ), tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Gene Information

human ... MKI67(4288)

说明

General description

Ki-67 (MRQ-64) is an antibody designed to target Ki-67 antigen-a nuclear protein encoded by the MKI67 gene whose presence correlates with G1, S, G2, and the mitotic phases of the cell cycle.¹ Though its specific role is largely postulated and still yet to be determined, Ki-67′s presence during cellular division makes it an excellent target for labeling rapidly growing malignancies.² Given that its presence correlates with cell proliferation, the immunohistochemical labeling of Ki-67 antigen may be useful in characterizing a lesion′s growth fraction. It has been demonstrated that identifying this antigen by IHC is useful in characterizing lesions of the breast, lymphoid cells, astrocytes, and uterus.^3-9

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

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Note: This IFU may not apply to your specific product lot.

Analysis Note

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Ki-67 Positive Control Slides, Product No. 275S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c