280C-1
Mammaglobin Cocktail (304-1A5 & 31A5)
Mouse & Rabbit Cocktail Antibody
别名:
Mammaglobin Cocktail (304-1A5 & 31A5) Mouse/Rabbit Monoclonal Antibodies
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
304-1A5/31A5, monoclonal
Application:
IHC
Citations:
6
biological source
mouse, rabbit
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
304-1A5/31A5, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart).
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (280C-14-ASR), vial of 0.5 mL concentrate (280C-15-ASR), bottle of 1.0 mL predilute (280C-17-ASR), vial of 1.0 mL concentrate (280C-16-ASR), bottle of 7.0 mL predilute (280C-18-ASR)
concentration
0.01-1 μg/mL (predilute), 2-270 μg/mL (concentrate)
technique(s)
immunohistochemistry: 1:100-1:500
isotype
IgG1, IgG
shipped in
wet ice
storage temp.
2-8°C
Gene Information
human ... SCGB2A2(4250)
General description
Mammaglobin (10 kD) is a breast-associated glycoprotein distantly related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin mRNA is present in high levels in human breast cancer cell lines, which has been shown to be a sensitive marker of breast cancer. When combined with other breast-restricted markers such as GCDFP-15, an overall sensitivity for breast carcinoma of 84% has been achieved. Anti-Mammaglobin can also be used to determine breast origin in the setting of metastatic carcinoma.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
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Download the latest released IFU
Note: This IFU may not apply to your specific product lot.
Note: This requires a keycode which can be found on your packaging or product label.
Download the latest released IFU
Note: This IFU may not apply to your specific product lot.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
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Zhiqiang Wang et al.
International journal of clinical and experimental pathology, 2(4), 384-389 (2009-01-23)
Identification of metastasis and occult micrometastases of breast cancer demands sensitive and specific diagnostic markers. In this study, we assessed the utility of a mouse monoclonal antibody to human mammaglobin for one such purpose. Immunohistochemical stains were performed on paraffin-embedded
Jae-Ho Han et al.
Archives of pathology & laboratory medicine, 127(10), 1330-1334 (2003-10-03)
Organ specificity is a desirable property of a tumor marker, especially in metastatic adenocarcinomas of unknown primary origin. Mammaglobin, a mammary-specific member of the uteroglobin family, is known to be overexpressed in human breast cancer. We investigated mammaglobin A expression
T P Fleming et al.
Annals of the New York Academy of Sciences, 923, 78-89 (2001-02-24)
The mammaglobin gene encodes a 10-kDa glycoprotein that is distantly related to a family of proteins that includes rat estramustine binding protein (EMBP)/prostatein and human Clara cell 10-kDa protein (CC10)/uteroglobin. Among normal adult tissues, mammaglobin mRNA expression has been detected
Eiichi Sasaki et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 20(2), 208-214 (2006-12-29)
Previously, we used the reverse transcription-polymerase chain reaction (RT-PCR) to show that mammaglobin (MGB1) can serve as a differential marker of breast cancer metastasis from primary lung cancer. However, mRNA-based methods are not appropriate for use in clinical practices. In
Rohit Bhargava et al.
American journal of clinical pathology, 127(1), 103-113 (2006-12-06)
There are limited data that compare the usefulness of mammaglobin with gross cystic disease fluid protein-15 (GCDFP-15) in the identification of breast carcinomas. Whole tissue sections of 29 breast carcinomas with matched lymph node metastases and 63 breast carcinomas on
商品
免疫组织化学（免疫组化，IHC）用于表征所有组织中的细胞内蛋白质或各种细胞表面。个体标记，或更常用的各种标记蛋白质组，可用于表征各种肿瘤亚型，确定原发组织，区分转移性肿瘤和原发性肿瘤，并提供可能对预后有重要意义、预测对治疗的响应、或评估残留肿瘤后处理的其他信息。
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