Quality Level
assay
≥95% (HPLC)
form
powder
color
yellow
mp
214-215 °C (lit.)
SMILES string
Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3ccccc3
InChI
1S/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H
InChI key
VCCRNZQBSJXYJD-UHFFFAOYSA-N
Gene Information
human ... ADORA2A(135), ADORA3(140), CYP1A2(1544)
rat ... Adora1(29290), Adora2a(25369)
General description
高良姜精是从姜科家族成员中分离出的一种类黄酮,主要用作草药。
Application
高良姜素已用于:
- 作为试验药物用于测试其在顺铂诱导的肾毒性啮齿动物模型中的改善作用
- 测试其对3T3-L1前脂肪细胞向脂肪细胞分化的影响
- 作为核磁共振波谱和质谱的内标物
Biochem/physiol Actions
高良姜精具有抗氧化、抗凋亡、抗炎和抗肥胖特性。此外,它还具有抵抗环境和饮食致癌物的抗遗传毒性。高良姜精通过阻止癌细胞增殖、诱导凋亡和自噬以及抑制转移来抑制癌细胞生长。高良姜精还具有抑制CYP1A1(细胞色素P450,家族成员1A1)活性的能力。
Still not finding the right product?
Explore all of our products under 高良姜黄素
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
商品
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子(如铁、铜和镉)引起的氧化损伤。
Chemopreventive mechanisms of galangin against hepatocellular carcinoma: A review
Fang D, et al.
Biomedicine and Pharmacotherapy, 109(11), 2054-2061 (2019)
Yohan Seo et al.
PloS one, 12(3), e0174935-e0174935 (2017-04-01)
Anoctamin 1 (ANO1), a calcium-activated chloride channel, is highly amplified in prostate cancer, the most common form of cancer and leading causes of cancer death in men, and downregulation of ANO1 expression or its functional activity is known to inhibit
Brinda Balasubramanian et al.
Molecules (Basel, Switzerland), 27(14) (2022-07-28)
Cholangiocarcinoma (CCA) is a heterogenous group of malignancies in the bile duct, which proliferates aggressively. CCA is highly prevalent in Northeastern Thailand wherein it is associated with liver fluke infection, or Opisthorchis viverrini (OV). Most patients are diagnosed in advanced
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 282200-25MG | 04061826227664 |
| 282200-100MG | 04061826227626 |
