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Merck
CN

302-05A

Human Pulmonary Artery Endothelial Cells: HPAEC, adult

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关于此项目

NACRES:
NA.81
UNSPSC Code:
41106514
Biological source:
human pulmonary artery (normal)
Growth mode:
Adherent
Morphology:
Endothelial
Relevant disease(s):
diabetes; cardiovascular diseases
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biological source

human pulmonary artery (normal)

packaging

pkg of 500,000 cells

manufacturer/tradename

Cell Applications, Inc

growth mode

Adherent

karyotype

2n = 46

morphology

Endothelial

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

diabetes; cardiovascular diseases

shipped in

dry ice

storage temp.

−196°C

Quality Level

General description

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

HPAEC provide an excellent model system to study many aspects of cardiovascular function and disease, including diabetes-associated complications, mechanisms of endothelial dysfunction caused by environment, oxidative stress, hypoxia and inflammation, as well as mode of action of various natural compounds and drug candidates.

Application

cardiovascular function, screening of drug candidates, angiogenesis, vasodilator function, transport of deoxygenated bloood from heart to lungs

Biochem/physiol Actions

Artery

Preparation Note

  • 2nd passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 15 doublings

Please refer to the HPAEC Culture Protocol.

Other Notes

Basal Medium containing 10% FBS & 10% DMSO

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mauro Lago-Docampo et al.
Frontiers in cardiovascular medicine, 9, 823133-823133 (2022-03-15)
Pulmonary Arterial Hypertension (PAH) is a rare disease caused by the obliteration of the pulmonary arterioles, increasing pulmonary vascular resistance and eventually causing right heart failure. Endothelin-1 (EDN1) is a vasoconstrictor peptide whose levels are indicators of disease progression and

实验方案

Technical information for working with human pulmonary artery endothelial cells including thawing, subculturing and cryopreservation

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