biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
2F11, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (302M-14)
vial of 0.5 mL concentrate (302M-15)
bottle of 1.0 mL predilute (302M-17)
vial of 1.0 mL concentrate (302M-16)
bottle of 7.0 mL predilute (302M-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
isotype
IgG1κ
control
brain
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... NEFL(4747)
Other Notes
Neurofilament Positive Control Slides, Product No. 302S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
Analysis Note
 IVD |  IVD |  IVD |  RUO |
General description
Anti-neurofilament stains an antigen localized in a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
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S R Dubovy et al.
The British journal of ophthalmology, 85(8), 949-951 (2001-07-24)
Palisaded encapsulated neuroma of the skin (PEN) is an uncommon benign neural tumour that occurs on the head and neck, including the eyelid, but is unfamiliar to many ophthalmic clinicians. For the first time in the ophthalmic literature, the clinical
G N van Muijen et al.
The American journal of pathology, 116(3), 363-369 (1984-09-01)
Three monoclonal antibodies, one directed against cytokeratin (clone 80) and two directed against neurofilament (clones 2F11 and 3G6), were used in the study of a series of 77 lung carcinomas by immunohistochemical staining. The anti-cytokeratin antibody, a very broadly reacting
J N Wood et al.
Bioscience reports, 1(3), 263-268 (1981-03-01)
Hybrid cell lines secreting monoclonal antibodies against mammalian neurofilaments have been prepared. An improved protocol for the preparation of neurofilaments and methods for the identification and isolation of such hybridomas are presented. The antibodies produced specifically stain only neuronal
Irma E Erana-Rojas et al.
Annals of diagnostic pathology, 6(5), 265-271 (2002-10-12)
Demyelinating disease presenting as a solitary contrast-enhancing mass poses a diagnostic challenge for both radiologists and surgical pathologists. We report the cases of two female patients, aged 23 and 37 years, who exhibited the clinical and radiologic features of a
Protease inhibitors of human plasma. Alpha 1-antichymotrypsin.
R W Berninger
Journal of medicine, 16(1-3), 101-128 (1985-01-01)
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