30564
Trehalose 6-hexadecanoate
≥95.0% (GC)
别名:
α,α-Trehalose 6-palmitate, α-D-Glucopyranosyl-α-D-glucopyranoside 6-hexadecanoate, 6-O-Palmitoyl-α,α-trehalose, Trehalose 6-palmitate
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经验公式（希尔记法）:
C28H52O12
化学文摘社编号:
分子量:
580.71
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25
SMILES string
O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@H]2O[C@H](COC(CCCCCCCCCCCCCCC)=O)[C@@H](O)[C@H](O)[C@H]2O
InChI
1S/C28H52O12/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(30)37-17-19-22(32)24(34)26(36)28(39-19)40-27-25(35)23(33)21(31)18(16-29)38-27/h18-19,21-29,31-36H,2-17H2,1H3/t18?,19?,21-,22-,23?,24?,25+,26+,27-,28-/m1/s1
InChI key
VNHFMAKRYDWMAF-DHFWNHDGSA-N
assay
≥95.0% (GC)
form
powder
mol wt
580.71 g/mol
CMC
0.0061 mM
storage temp.
2-8°C
Application
Trehalose is commonly used as a stabilizer and protective material for biomaterial compounds. Because of these characteristics, Trehalose is introduced as a hydrophilic part. Due to these properties of Trehalose, protein degeneration is expected to be prevented with Trehalose detergents. Therefore, Trehalose detergents may keep the function of the protein and be utilized in the field of proteomics research.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Nawal K Paul et al.
The Journal of organic chemistry, 78(2), 363-369 (2012-12-12)
It was shown that reaction of trehalose with 1 equiv of a fatty acid in pyridine promoted by 1 equiv of the uronium-based coupling agent 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) at room temperature gives a good yield of the primary ester accompanied
A K Datta et al.
Carbohydrate research, 218, 95-109 (1991-09-30)
A simplified synthesis of 6-mono- and 6,6'-di-corynomycolate esters of alpha,alpha-trehalose, and related compounds, was achieved by coupling the (hydroxyl-protected) acids to the partially trimethylsilylated sugar in the presence of dicyclohexylcarbodiimide and 4-dimethylaminopyridine. As acid reactants, (2-RS,3-RS)-3-hydroxy-2-tetradecyloctadecanoic acid (DL-corynomycolic acid) and
L Schiefelbein et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 76(3), 342-350 (2010-09-08)
Nonionic polyethylene glycol-derived surfactants are today's choice as surfactants in protein formulations. Different groups discovered that although surface-induced stresses are reduced by these excipients, the long-term stability of different proteins decreased due to polyethylene glycol-related induction of oxidation processes under
Chemical and biochemical studies on carbohydrate esters. V. Anti Ehrlich ascites tumor effect and chromatographic behaviors of fatty acyl monoesters of sucrose and trehalose.
Y Nishikawa et al.
Chemical & pharmaceutical bulletin, 25(7), 1717-1724 (1977-07-01)
Surface activities of monoacyl trehaloses in aqueous solution.
Chen, J., et al.
Food Sci. Technol., 40, 412-417 (2006)
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