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Merck
CN

30906

蓖麻油,乙氧基化

别名:

PEG-35 蓖麻油, 聚氧乙烯蓖麻油

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化学文摘社编号:
UNSPSC Code:
12161900
NACRES:
NA.25
MDL number:
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SMILES string

ClCC(OC(=O)N)CCl

InChI

1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)

InChI key

JMNCUXPHXKHBPY-UHFFFAOYSA-N

description

non-ionic

form

paste

impurities

alkalinity, complies, ≤ acetic acid (≤0.5 g/100g (%) verfied on random samples only), ≤0.1% oleic acid, ≤0.1% palmitic acid, ≤0.2% sulfated ash (verfied on random samples only), ≤0.20% ricinoleic acid, ≤0.5% water, ≤1 ppm ethylene oxide (verfied on random samples only), ≤1.0% free fatty acids, ≤10 ppm dioxan (verfied on random samples only), ≤10 ppm heavy metals (verfied on random samples only), ≤620 ppm diethylene glycol (verfied on random samples only), ≤620 ppm ethylene glycol (verfied on random samples only)

ign. residue

≤0.2%

pH

5.0-7.0 (1 g/10 mL in H2O)

viscosity

600-750 mPa.s(25 °C)

acid value

≤2.0 mg KOH/g

hydroxyl value

65‑78 mg KOH/g

iodine value

25‑35 g/100g

saponification value

65‑70 mg KOH/g

cation traces

K: ≤15 ppm

Quality Level

Application

乙氧基化蓖麻油可用于乳化和溶解油类和其它不溶于水的物质。 与乙氧基化蓖麻油相似,但含水量较低,且粘度不同。

Analysis Note

相对密度 D (25/25) 1.05-1.06

Legal Information

Cremophor is a registered trademark of BASF SE

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

494.6 °F - Not applicable

flash_point_c

257 °C - Not applicable


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分析证书(COA)

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Ravouru Nagaraju et al.
Current drug discovery technologies, 6(4), 299-305 (2009-12-23)
The core-in-cup matrix tablets of Metoprolol succinate were prepared by wet granulation technique. Of all the investigated formulations, the optimized formulation of MS-09 followed zero-order kinetics of drug release. Trail on MS-09 was formulated using 7.5% hydrogenated castor-oil (HCO) and
Hideki Ichikawa et al.
Current drug delivery, 4(2), 131-140 (2007-04-26)
The effects of the formulation and particle composition of gadolinium (Gd)-containing lipid nanoemulsion (Gd-nanoLE) on the biodistribution of Gd after its intravenous (IV) injection in D(1)-179 melanoma-bearing hamsters were evaluated for its application in cancer neutron-capture therapy. Gd-nanoLEs whose particles
Enas A Mahmoud et al.
AAPS PharmSciTech, 10(1), 183-192 (2009-02-25)
The purpose of this study was to combine the advantages of self-nanoemulsifying drug delivery systems and tablets as a conventional dosage form emphasizing the excipients' effect on the development of a new dosage form. Systems composed of HCO-40, Transcutol HP
Siva Narayanan et al.
Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society, 32(3), 163-170 (2005-06-03)
This study compared clinical outcomes and nursing labor costs associated with (a) balsam Peru, hydrogenated castor oil, and trypsin (BCT) ointment; (b) BCT + Other; and (c) Other treatments in 2014 wound episodes occurring in 861 patients (mean 2.34 wounds/patient).
Kumiko Ueda et al.
Journal of drug targeting, 11(1), 37-43 (2003-07-11)
Lipid emulsions with particle sizes of 190-270 nm were prepared with soybean oil (SO) and a series of hydrogenated castor oils (HCOs) with various oxyethylene numbers, and the effect of oxyethylene numbers of HCOs on the pharmacokinetics of menatetrenone incorporated

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