biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
PASE/4LJ, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (326M-14), vial of 0.5 mL concentrate (326M-15), bottle of 1.0 mL predilute (326M-17), vial of 1.0 mL concentrate (326M-16), bottle of 7.0 mL predilute (326M-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
isotype
IgG1
control
prostate
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... PSAP(5660)
General description
Anti-PSAP reacts with prostatic acid phosphatase in the glandular epithelium of normal and hyperplastic prostate, carcinoma of the prostate, and metastatic cells of prostatic carcinoma. This marker may be helpful in pinpointing the site of origin in cases of metastatic carcinoma of the prostate, and is considered a more sensitive marker than PSA. However, it also offers less specificity. Nevertheless, PSAP complements PSA in the right clinical context.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
![]() IVD | ![]() IVD | ![]() IVD | ![]() RUO |
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
PSAP Positive Control Slides, Product No. 326S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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此项目有
J H van Krieken
The American journal of surgical pathology, 17(4), 410-414 (1993-04-01)
A 66-year-old man presented with a mass just behind the lower part of the left ear. A biopsy showed a moderately differentiated adenocarcinoma that was prostate-specific antigen (PSA)- and prostate-specific acid phosphatase (PSAP)-positive. This finding suggested a metastasis of a
E M Genega et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 13(11), 1186-1191 (2000-12-06)
Morphologic features alone can usually be used to distinguish prostatic adenocarcinoma and urothelial carcinoma of the urinary bladder. Poorly differentiated tumors, however, can occasionally have features of both neoplasms, making determination of site of origin difficult. No study has provided
J I Epstein
The Urologic clinics of North America, 20(4), 757-770 (1993-11-01)
This article describes the immunoreactivity of PSA and PAP in non-neoplastic and neoplastic prostate tissue. Listed are examples of cross reactivity of PSA and PAP in non-neoplastic and neoplastic tissue from other organs. The use of PSA and PAP to
N Kimura et al.
Virchows Archiv. A, Pathological anatomy and histopathology, 410(3), 247-251 (1986-01-01)
Although prostate-specific acid phosphatase (PASP) has been recognized as a specific marker of tissue of prostatic origin, several investigators have pointed out that some of the carcinoid tumours and islet cell tumours of the pancreas reacted immunohistochemically to PSAP. We
M A Ansari et al.
American journal of clinical pathology, 76(1), 94-98 (1981-07-01)
An unusual case of carcinoma of the prostate with metastases is described. the prostate and the metastases showed adenocarcinoma with carcinoid-like areas. A tumor with the same histologic features was found at the tip of the appendix and proved to
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