biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
PASE/4LJ, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (326M-14)
vial of 0.5 mL concentrate (326M-15)
bottle of 1.0 mL predilute (326M-17)
vial of 1.0 mL concentrate (326M-16)
bottle of 7.0 mL predilute (326M-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
isotype
IgG1
control
prostate
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... PSAP(5660)
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
Analysis Note
 IVD |  IVD |  IVD |  RUO |
General description
Anti-PSAP reacts with prostatic acid phosphatase in the glandular epithelium of normal and hyperplastic prostate, carcinoma of the prostate, and metastatic cells of prostatic carcinoma. This marker may be helpful in pinpointing the site of origin in cases of metastatic carcinoma of the prostate, and is considered a more sensitive marker than PSA. However, it also offers less specificity. Nevertheless, PSAP complements PSA in the right clinical context.
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
PSAP Positive Control Slides, Product No. 326S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
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N Kuroda et al.
Pathology international, 49(5), 457-461 (1999-07-27)
Signet-ring cell carcinoma (SRCC) of the prostate is a very rare neoplasm and there have been only 38 cases reported to date. Here the 39th case of prostatic SRCC containing a small amount of neutral mucin, prostatic specific antigen (PSA)
Immunohistochemistry of prostatic acid phosphatase.
M Nadji et al.
Annals of the New York Academy of Sciences, 390, 133-141 (1982-01-01)
Noman Kidwai et al.
Breast cancer research : BCR, 6(1), R18-R23 (2003-12-19)
The androgen-regulated proteins prostate-specific antigen (PSA) and prostate-specific acid phosphatase (PSAP) are present in high concentrations in normal prostate and prostatic cancer and are considered to be tissue-specific to prostate. These markers are commonly used to diagnose metastatic prostate carcinoma
L K Green et al.
Human pathology, 22(3), 242-246 (1991-03-01)
Since the introduction of hormonal therapy for the treatment of metastatic prostatic adenocarcinoma, there have been 33 reports of metastases of prostate carcinoma to the breast. We report two cases of diethylstilbestrol (DES)-treated patients with metastatic prostate adenocarcinoma who developed
A A Elgamal et al.
Urology, 44(1), 84-90 (1994-07-01)
The aim of the study was to explore possible production of prostate-specific markers by the embryologically and physiologically related accessory male sex glands, other than the prostate. The accessory male sex glands of Cowper, Littre, and Morgagni were studied systematically
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