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Merck
CN

333M-1

Spectrin (RBC2/3D5) Mouse Monoclonal Antibody

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
RBC2/3D5, monoclonal
Application:
immunohistochemistry (formalin-fixed, paraffin-embedded sections)
Species reactivity:
human
Citations:
4
Technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10-1:100
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biological source

mouse

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

RBC2/3D5, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (333M-14)
vial of 0.5 mL concentrate (333M-15)
bottle of 1.0 mL predilute (333M-17)
vial of 1.0 mL concentrate (333M-16)
bottle of 7.0 mL predilute (333M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10-1:100

isotype

IgG1κ

control

bone marrow

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Quality Level

Gene Information

human ... SPTA1(6708)

Analysis Note


IVD

IVD

IVD

RUO

General description

Spectrin is a cytoskeletal protein which is found in muscles, red blood cells and red cell precursors. Anti-Spectrin antibody is useful in the diagnosis of erythroid leukemias.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Spectrin Positive Control Slides, Product No. 333S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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V Nehls et al.
The American journal of pathology, 142(5), 1565-1573 (1993-05-01)
Expression of the erythrocyte anion exchanger band 3, and ankyrin and spectrin, two cytoskeletal proteins of the red blood cell membrane, was studied by immunofluorescence using: 1) smears of human bone marrow from healthy donors and from a patient with
M Müller et al.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine, 48(1), 51-57 (2001-08-23)
In an immunohistological/cytological study of canine bone marrow, the aim was to demonstrate canine erythroid cells with the help of various commercially available antibodies against human antigens (monoclonal antibody against glycophorin A, polyclonal antibodies against haemoglobin and spectrin). In order
N Terada et al.
Journal of anatomy, 190 ( Pt 3), 397-404 (1997-04-01)
A quick-freezing and deep-etching method in combination with erythrocyte splitting was used to examine the cytoplasmic aspect of whole-mount human erythrocyte membranes. Various external forces induced alterations in membrane skeletal organisation during the splitting procedure. The initial change was elongation
Y Sadahira et al.
Journal of clinical pathology, 52(12), 919-921 (2000-03-11)
To investigate whether spectrin can be used as an immunohistochemical marker for erythroid precursors in routinely processed paraffin embedded bone marrow sections. Bone marrow biopsies and clot sections were stained with rabbit antihuman erythrocyte spectrin antibodies, specific for erythroid cells

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