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337M-8

TAG-72 (B72.3) Mouse Monoclonal Antibody

Name: TAG-72 (B72.3) Mouse Monoclonal Antibody
Brand: SIGMA

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关于此项目

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

B72.3, monoclonal

Application:

IHC (p)

Citations:

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属性

biological source

mouse

Quality Level

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

B72.3, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (337M-84), vial of 0.5 mL concentrate (337M-85), bottle of 1.0 mL predilute (337M-87), vial of 1.0 mL concentrate (337M-86), bottle of 7.0 mL predilute (337M-88)

manufacturer/tradename

Cell Marque^®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG1κ

control

lung adenocarcinoma

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

说明

General description

Anti-B72.3 recognizes a high molecular weight glycoprotein called TAG-72 that is present in human adenocarcinomas and in lesser amounts, non-neoplastic tissues. It has also been found to be useful to distinguish between mesothelioma and adenocarcinoma, however, false positive reactions can occur so results must be interpreted with the utmost caution.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

TAG-72 Positive Control Slides, Product No. 337S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Lot/Batch Number

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Use of a monoclonal antibody (B72.3) as a novel immunohistochemical adjunct for the diagnosis of carcinomas in fine needle aspiration biopsy specimens.

W W Johnston et al.

Human pathology, 17(5), 501-513 (1986-05-01)

Monoclonal antibody B72.3 has been shown to be reactive with a high-molecular-weight glycoprotein complex termed TAG(tumor-associated glycoprotein)-72. By the avidin-biotin immunoperoxidase method, fine needle aspirates and corresponding surgically excised tumor tissues from both malignant and benign tissues were analyzed for

Distribution of tumor-associated glycoprotein-72 (TAG-72) expression throughout the normal female reproductive tract.

K G Osteen et al.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 11(3), 216-220 (1992-07-01)

Compared with the degree of investigation of stage-specific expression of tumor-associated glycoprotein-72 (TAG-72) in fundal endometrium, other regions of the female reproductive tract have not received comparable attention. Regional, cell-type-specific, and temporal differences in estrogen receptor and progesterone receptor distribution

Monoclonal antibody B72.3 as a diagnostic adjunct in fine needle aspirates of breast masses.

J Lundy et al.

Annals of surgery, 203(4), 399-402 (1986-04-01)

Fine needle aspirations of breast masses were evaluated to establish a cytologic diagnosis. In 45 cases, the sensitivity was 73%, specificity 100%, and diagnostic accuracy 84%. Fifty cases (27 malignant and 23 benign) were evaluated by immunoperoxidase staining of the

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全球贸易项目编号

货号	GTIN
337M-84	0841683136927
337M-85	0841683136934
337M-88	0841683136965
337M-86	0841683136941
337M-86-RUO	04061836532666
337M-87	0841683136958