34025
双溴二胺
BioReagent, suitable for fluorescence, ≥95.0% (CHN)
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关于此项目
经验公式（希尔记法）:
C10H10Br2N2O2
化学文摘社编号:
分子量:
350.01
Beilstein:
4189453
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.32
产品线
BioReagent
质量水平
方案
≥95.0% (CHN)
mp
170-172 °C (lit.)
溶解性
DMF: soluble
acetonitrile: soluble
chloroform: soluble
荧光
λex 391 nm in methanol
λex 393 nm; λem 477 nm in 0.1 M Tris pH 7.0, gutathione red
适用性
suitable for fluorescence
储存温度
2-8°C
SMILES字符串
CC1=C(CBr)N2N(C1=O)C(=O)C(C)=C2CBr
InChI
1S/C10H10Br2N2O2/c1-5-7(3-11)13-8(4-12)6(2)10(16)14(13)9(5)15/h3-4H2,1-2H3
InChI key
OSIYFMVMZXJKSP-UHFFFAOYSA-N
应用
Dibromobimane是一种双官能化硫醇试剂，用作半胱氨酸谱图和研究蛋白质结构/构象及交联过程的交联剂。
包装
无底玻璃瓶。内含物在插入的融合锥体内。
其他说明
荧光硫醇特异性标记试剂
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Zhenhui Chen et al.
The Journal of biological chemistry, 281(20), 14163-14172 (2006-03-24)
Interactions between the transmembrane domains of phospholamban (PLB) and the cardiac Ca2+ pump (SERCA2a) have been investigated by chemical cross-linking. Specifically, C-terminal, transmembrane residues 45-52 of PLB were individually mutated to Cys, then cross-linked to V89C in the M2 helix
Hai Po Helena Liang et al.
The Biochemical journal, 437(3), 455-460 (2011-05-21)
TF (tissue factor) is a transmembrane cofactor that initiates blood coagulation in mammals by binding Factor VIIa to activate Factors X and IX. The cofactor can reside in a cryptic configuration on primary cells and de-encryption may involve a redox
E Kim et al.
Journal of molecular biology, 299(2), 421-429 (2000-06-22)
The DNase I binding loop (residues 38-52), the hydrophobic plug (residues 262-274), and the C terminus region are among the structural elements of monomeric (G-) actin proposed to form the intermonomer interface in F-actin. To test the proximity and interactions
Yung-Feng Lin et al.
The Journal of biological chemistry, 282(23), 16783-16791 (2007-04-19)
The ArsA ATPase is the catalytic subunit of the ArsAB pump encoded by the arsRDABC operon of Escherichia coli plasmid R773. ArsD is a metallochaperone that delivers As(III) to ArsA, increasing its affinity for As(III), thus conferring resistance to environmental
T W Loo et al.
The Journal of biological chemistry, 275(50), 39272-39278 (2000-10-03)
P-glycoprotein (P-gp) can transport a wide variety of cytotoxic compounds that have diverse structures. Therefore, the drug-binding domain of the human multidrug resistance P-gp likely consists of residues from multiple transmembrane (TM) segments. In this study, we completed cysteine-scanning mutagenesis
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