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Merck
CN

342R-1

Tryptase (EP259) Rabbit Monoclonal Primary Antibody

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关于此项目

UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
EP259, monoclonal
Application:
IHC (p)
Citations:
2

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biological source

rabbit

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EP259, monoclonal

description

For In Vitro Diagnostic Use in Select Regions

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (342R-14), vial of 0.1 mL concentrate Research Use Only (342R-14-RUO), vial of 0.5 mL concentrate (342R-15), vial of 1.0 mL concentrate (342R-16), vial of 1.0 mL concentrate Research Use Only (342R-16-RUO), vial of 1.0 mL pre-dilute Research Use Only (342R-17-RUO), vial of 1.0 mL pre-dilute ready-to-use (342R-17), vial of 7.0 mL pre-dilute ready-to-use (342R-18), vial of 7.0 mL pre-dilute ready-to-use Research Use Only (342R-18-RUO)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:200 (concentrated)

isotype

IgG

control

uterus

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... TPSAB1(7177)

相关类别

General description

Tryptases compose a subfamily of proteinases with trypsin-like activity that are mostly stored in mast cell secretory granules and released into the extracellular environment upon mast cell activation. Several biological functions for tryptases have been proposed, including involvement in inflammatory and allergic responses. Mature mast cells have a complex distribution throughout the body. Anti-tryptase is a useful marker for mast cells.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Analysis Note


IVD
IVD
IVD
RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Tryptase Positive Control Slides, Product No. 342S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000139001
0000119585
0000082108
0000082053
0000082107

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I S Roberts et al.
Journal of clinical pathology, 53(11), 858-862 (2000-12-29)
Mast cells, when activated, secrete a large number of fibrogenic factors and have been implicated in the development of fibrotic conditions of the liver, lung, and skin. There is evidence that renal fibrosis is closely linked with a chronic inflammatory
L Fiorucci et al.
Cellular and molecular life sciences : CMLS, 61(11), 1278-1295 (2004-06-02)
Tryptases constitute a subfamily of trypsin-like proteinases, stored in the mast cell secretory granules of all mammalian organisms. These enzymes are released along with other mediators into the extracellular medium upon mast cell activation/degranulation. Among the trypsin-like enzymes, tryptases are

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