biological source
mouse
conjugate
unconjugated
antibody form
diluted ascites fluid
antibody product type
primary antibodies
clone
CWWB1, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (346M-14), vial of 0.5 mL concentrate (346M-15), bottle of 1.0 mL predilute (346M-17), vial of 1.0 mL concentrate (346M-16), bottle of 7.0 mL predilute (346M-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
isotype
IgG1
control
colon
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... VIL1(7429)
General description
Villin is a 95 kD glycoprotein of microvilli associated with rootlet formation in gastrointestinal mucosal epithelium. Anti-villin labels the brush border area in the gastrointestinal mucosal epithelium. This antibody has been useful in differentiating gastrointestinal adenocarcinoma, neuroendocrine carcinomas, and ovarian adenocarcinomas from adenocarcinomas of other organs. This antibody also labels Merkel cells of the skin.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Villin Positive Control Slides, Product No. 346S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.
结直肠癌是男性和女性中第三大常见癌症。预计2016年将发生136,000例结直肠癌。
Satoshi Nishizuka et al.
Cancer research, 63(17), 5243-5250 (2003-09-23)
Colon and ovarian cancers can be difficult to distinguish in the abdomen, and the distinction is important because it determines which drugs will be used for therapy. To identify molecular markers for that differential diagnosis, we developed a multistep protocol
N S Goldstein et al.
American journal of clinical pathology, 116(3), 319-325 (2001-09-14)
We studied 14 mucinous and 26 nonmucinous bronchioloalveolar adenocarcinomas (BACs) with thyroid transcription factor (TTF), cytokeratin (CK) 7, CK20, and villin to characterize their staining patterns with these antibodies and identify staining differences between the neoplasms. We also stained 11
Pheroze Tamboli et al.
Archives of pathology & laboratory medicine, 126(9), 1057-1063 (2002-09-03)
To determine whether a limited immunohistochemical panel can help differentiate metastatic colonic adenocarcinoma from primary enteric-type adenocarcinoma of the urinary tract and urothelial (transitional cell) carcinoma with glandular differentiation, which appear morphologically similar but most often necessitate different treatment protocols.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 346M-16-RUO | 04061836567996 |
| 346M-14 | 0841683137573 |
| 346M-16 | 0841683137597 |
| 346M-17 | 0841683137603 |
| 346M-18 | 0841683137610 |
| 346M-15 | 0841683137580 |