生物来源
mouse
偶联物
unconjugated
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
V9, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
表单
buffered aqueous solution
种属反应性
human
包装
vial of 0.1 mL concentrate (347M-14)
vial of 0.5 mL concentrate (347M-15)
bottle of 1.0 mL predilute (347M-17)
vial of 1.0 mL concentrate (347M-16)
bottle of 7.0 mL predilute (347M-18)
制造商/商品名称
Cell Marque®
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
同位素/亚型
IgGκ
控制
tonsil
运输
wet ice
储存温度
2-8°C
可视化
cytoplasmic
基因信息
human ... VIM(7431)
相关类别
一般描述
Anti-vimentin is of limited value as a diagnostic tool; however, when used in combination with other antibodies (in panels) it is useful for the subclassification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. This antibody recognizes a 57 kD intermediate filament. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
分析说明
 IVD |  IVD |  IVD |  RUO |
其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Vimentin Positive Control Slides, Product No. 347S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
法律信息
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
M Leader et al.
Histopathology, 11(1), 63-72 (1987-01-01)
In this study we examined 198 sarcomas, 38 carcinomas, 13 'tumours with a spindle cell component' and 22 malignant melanomas with a commercial monoclonal vimentin antibody. All histopathological material was formalin fixed and paraffin embedded. The results show this antibody
A Ben-Ze'ev
The Journal of cell biology, 99(4 Pt 1), 1424-1433 (1984-10-01)
The expression of cytokeratins and vimentin was investigated in Madin-Darby bovine epithelial cells (MDBK) in culture under conditions of varied cell spreading and cell-cell contact. When extensive cell-cell contact was achieved by seeding cells at high density in monolayer, or
W G McCluggage
Histopathology, 40(4), 309-326 (2002-04-12)
Recent years have witnessed significant developments in the use of immunohistochemistry in diagnostic gynaecological pathology. This review details the most significant of these. In ovarian pathology, differential cytokeratin staining (CK7 and 20) assists in distinguishing between a primary ovarian adenocarcinoma
I Takeyoshi et al.
Hepato-gastroenterology, 47(36), 1611-1614 (2001-01-10)
Carcinosarcomas are rare tumors, which are usually composed of carcinomatous areas close to or intermixed with sarcomatous components. Only 6 cases of carcinosarcoma of the colon have been reported in the English literature previously. We describe the 7th case, an
David Virant et al.
Nature communications, 9(1), 930-930 (2018-03-04)
Dense fluorophore labeling without compromising the biological target is crucial for genuine super-resolution microscopy. Here we introduce a broadly applicable labeling strategy for fixed and living cells utilizing a short peptide tag-specific nanobody (BC2-tag/bivBC2-Nb). BC2-tagging of ectopically introduced or endogenous
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