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Merck
CN

3514-05A

Human Carotid Artery Smooth Muscle Cells: HCtASMC, adult

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关于此项目

NACRES:
NA.81
UNSPSC Code:
41106514
Biological source:
human carotid artery (normal)
Growth mode:
Adherent
Relevant disease(s):
stroke; cardiovascular diseases
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biological source

human carotid artery (normal)

packaging

pkg of 500,000 cells

manufacturer/tradename

Cell Applications, Inc

growth mode

Adherent

karyotype

23

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

stroke; cardiovascular diseases

storage temp.

−196°C

Quality Level

Application

cardiovascluar function, transfer of oxygenated blood to skull, brain, neck, face, effects of drugs

Biochem/physiol Actions

Artery

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

General description

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Human Carotid Artery Smooth Muscle Cells (HCtASMC) provide a useful in vitro system to study all aspects of cardiovascular function and disease, especially those related to mechanisms of hyperplasia and hypertrophy of intimal smooth muscle cells leading to vascular occlusion in atherosclerosis and stent restenosis.Characterization: positive for smooth muscle cell specific alpha-actin expression.

Other Notes

Basal Medium containing 10% FBS & 10% DMSO

Preparation Note

  • 2nd passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 10 doublings

Please refer to the HCtASMC Culture Protocol.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Till Seime et al.
Cells, 10(6) (2021-06-03)
Calcification is a prominent feature of late-stage atherosclerosis, but the mechanisms driving this process are unclear. Using a biobank of carotid endarterectomies, we recently showed that Proteoglycan 4 (PRG4) is a key molecular signature of calcified plaques, expressed in smooth

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