36799
7-(Diethylamino)coumarin-3-carboxylic acid
BioReagent, suitable for fluorescence, ≥98.0% (HPCE)
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关于此项目
经验公式（希尔记法）:
C14H15NO4
化学文摘社编号:
分子量:
261.27
Beilstein:
6145963
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.32
产品线
BioReagent
质量水平
方案
≥98.0% (HPCE)
mp
222-224 °C (dec.) (lit.)
溶解性
DMF: soluble
DMSO: soluble
荧光
λex 409 nm; λem 473 nm in 0.1 M Tris pH 9.0
适用性
suitable for fluorescence
SMILES字符串
CCN(CC)c1ccc2C=C(C(O)=O)C(=O)Oc2c1
InChI
1S/C14H15NO4/c1-3-15(4-2)10-6-5-9-7-11(13(16)17)14(18)19-12(9)8-10/h5-8H,3-4H2,1-2H3,(H,16,17)
InChI key
WHCPTFFIERCDSB-UHFFFAOYSA-N
应用
7-(Diethylamino)coumarin-3-carboxylic acid (7-DCCA) may be used to study its photophysical properties in various solvents and solvent mixtures and as a fluorescent label for amine modification and protein conjugation
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
其他说明
Fluorescent label for amine modification and protein conjugation
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Hui Zhang et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 69(4), 1136-1139 (2007-07-28)
The structure of 7-(N,N'-diethylamino)-coumarin-3-carboxylic acid (DCCA) was verified by single crystal X-ray crystallography. The UV-vis absorption and fluorescence of DCCA were discussed. The compound exhibits strong blue emission under ultraviolet light excitation. The molecular structure of DCCA was optimized using
J R Leisey et al.
The American journal of physiology, 267(2 Pt 2), H645-H653 (1994-08-11)
Quantitation of metabolic parameters using the technique of cardiac surface fluorescence is complicated by motion and changes in tissue absorption. Because ratio fluorescence methodology can be applied to eliminate motion-induced errors, in the current study, we used a ratio fluorescence
Intense blue fluorescence in a leucine zipper assembly.
Hiroshi Tsutsumi et al.
Chembiochem : a European journal of chemical biology, 12(5), 691-694 (2011-03-16)
E. Koller et al.
Appl. Fluoresc. Technol., 4, 18-18 (1992)
A Kakio et al.
The Journal of biological chemistry, 276(27), 24985-24990 (2001-05-09)
GM1 ganglioside-bound amyloid beta-protein (GM1/Abeta), found in brains exhibiting early pathological changes of Alzheimer's disease (AD) including diffuse plaques, has been suggested to be involved in the initiation of amyloid fibril formation in vivo by acting as a seed. To
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