biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
GS-6, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (389M-14)
vial of 0.5 mL concentrate (389M-15)
bottle of 1.0 mL predilute (389M-17)
vial of 1.0 mL concentrate (389M-16)
bottle of 7.0 mL predilute (389M-18)
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
isotype
IgG2a
control
hepatocellular carcinoma
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... GLUL(2752)
Analysis Note
 IVD |  IVD |  IVD |  RUO |
General description
Glutamine synthetase (GS) catalyzes the synthesis of glutamine from glutamate and ammonia in the mammalian liver. In normal liver, GS expression is seen in centrilobular (zone 3) hepatocytes, but not in mid-zone (zone 2) or periportal (zone 3) hepatocytes. Glutamine synthetase immunohistochemistry is also positive in neoplasms of hepatocyte origin, such as hepatocellular carcinoma (HCC) and hepatocellular adenoma, making it useful for identifying these tumors.
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Glutamine Synthetase Positive Control Slides, Product No. 389S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
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