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Merck
CN

39220

丹磺酰氯

suitable for fluorescence, BioReagent, ≥99.0% (HPLC)

别名:

1-二甲基氨基萘-5-磺酰氯, 5-(二甲基氨基)萘-1-磺酰氯, DNSCl, 氯化二硝基水杨酸, 5-(二甲基氨基)-萘-1-磺酰氯

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关于此项目

经验公式(希尔记法):
C12H12ClNO2S
化学文摘社编号:
分子量:
269.75
UNSPSC Code:
12352101
NACRES:
NA.32
PubChem Substance ID:
EC Number:
210-092-6
Beilstein/REAXYS Number:
2217205
MDL number:
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产品名称

丹磺酰氯, suitable for fluorescence, BioReagent, ≥99.0% (HPLC)

SMILES string

CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O

InChI key

XPDXVDYUQZHFPV-UHFFFAOYSA-N

InChI

1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3

product line

BioReagent

assay

≥99.0% (HPLC)

Quality Level

form

powder

mol wt

269.75 g/mol

composition

Carbon Content, 53.57%
Hydrogen Content, 4.49%
Nitrogen Content, 5.00%

concentration

≤100% (5-dimethylaminonaphthalene-1-sulphonyl chloride)

color

orange-yellow
light yellow to dark yellow
yellow-orange
light yellow-orange to dark orange

mp

72-74 °C (lit.)

solubility

acetone: 0.2 g/10 mL

fluorescence

λex 337 nm; λem 492 nm in chloroform (after derivatization with hexylamine)

suitability

suitable for fluorescence

storage temp.

2-8°C

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Application

一种用于氨基酸和肽的荧光N-末端衍生化的荧光试剂,并且可用反相HPLC进行检测。
丹磺酰氯用作衍生化试剂,用于临床前研究研究乙炔雌二醇的大量代谢和最低给药剂量。 使用丹磺酰氯获得衍生物通过HPLC方法测定人血清中双酚的研究。 丹磺酰氯衍生物适用于LC/MS测定和表征食品样品中草甘膦、氨甲基膦酸(AMPA)和草铵膦 。

General description

丹磺酰氯又称5-二甲基氨基萘-1-磺酰氯,是一种柱前衍生化试剂。 衍生化反应后,荧光衍生物可使用NMR、IR、UV-vis和荧光显微镜等多种分析方法分析。丹磺酰氯是一种典型的芳香族磺酰氯,它与各种碱反应,生成具有不同稳定性的衍生物。

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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