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Pyrimidine nucleoside phosphorylase

Name: Pyrimidine nucleoside phosphorylase
Brand: SIGMA

recombinant, expressed in E. coli, ≥1300 U/mL

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关于此项目

化学文摘社编号:

9055-35-0

MDL number:

MFCD00011685

UNSPSC Code:

12352204

NACRES:

NA.54

EC 号:

2.4.2.2 (BRENDA, IUBMB)

Specific activity:

≥1300 U/mL

Recombinant:

expressed in E. coli

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属性

recombinant

expressed in E. coli

Quality Segment

100

form

liquid

specific activity

≥1300 U/mL

relevant disease(s)

cancer

storage temp.

−20°C

说明

Application

Pyrimidine nucleoside phosphorylase (PyNPase) may be used as a marker to predict the malignant potential of breast cancer, especially lymph node metastasis. PyNPase is used to study breast cancer, specifically its role in angiogenesis.

Biochem/physiol Actions

Pyrimidine nucleoside phosphorylase (PyNPase) is a glycosyltransferase that catalyzes the conversion of pyrimidine nucleoside and phosphate to a pyrimidine base and α-D-ribose 1-phosphate. PyNPase plays a significant role in breast cancer angiogenesis.

Other Notes

One unit will convert 1 μmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per minute at pH 7.4 and 25°C

象形图

GHS08

警示词

Danger

危险代码

H334

预防性声明

P261 - P284 - P501

Hazard Classifications

Resp. Sens. 1

存储类别

12 - Non Combustible Liquids

怎么回事？

WGK 1

闪点 (F)

Not applicable

闪点 (°C)