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Merck
CN

40227

Sigma-Aldrich

6-十二酰基- N,N -二甲基-2-萘胺

suitable for fluorescence, ≥97.0% (HPLC)

别名:

2-（二甲氨基）-6-十二酰萘, N,N-二甲基-6-十二酰-2-萘胺, 劳丹

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关于此项目

经验公式（希尔记法）:
C24H35NO
CAS Number:
74515-25-6
分子量:
353.54
Beilstein:
7379104
MDL编号:
MFCD00467560
UNSPSC代码:
12352116
PubChem化学物质编号:
57649941
NACRES:
NA.32

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质量水平

100

方案

≥97.0% (HPLC)

mp

88 °C (lit.)

溶解性

DMF: soluble
acetonitrile: soluble
methanol: soluble

荧光

λex 366 nm; λem 497 nm in methanol

适用性

suitable for fluorescence

SMILES字符串

CCCCCCCCCCCC(=O)c1ccc2cc(ccc2c1)N(C)C

InChI

1S/C24H35NO/c1-4-5-6-7-8-9-10-11-12-13-24(26)22-15-14-21-19-23(25(2)3)17-16-20(21)18-22/h14-19H,4-13H2,1-3H3

InChI key

JHDGGIDITFLRJY-UHFFFAOYSA-N

相关类别

应用

6-十二酰基- N,N -二甲基-2-萘胺 (Laurdan) 是一种用于研究膜结构、顺序和流动性等动态过程的荧光探针。

包装

无底玻璃瓶。内含物装在插入的融合锥内。

其他说明

荧光膜探针

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN6362
BCCL3472
BCCK1834
BCCH5141
BCCF8218

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the appearance of Product No. 40227 (6-Dodecanoyl-N,N-dimethyl-2-naphthylamine, also known as Laurdan)?

    Product 40227 (6-Dodecanoyl-N,N-dimethyl-2-naphthylamine) is described as powder to fine flakes.

  6. What is the solubility of Product No. 40227(6-Dodecanoyl-N,N-dimethyl-2-naphthylamine, also known as Laurdan)?

    Product 40227 (6-Dodecanoyl-N,N-dimethyl-2-naphthylamine) is soluble in N,N-dimethylformamide (DMF), methanol and acetonitrile.  It is also reported to be soluble in chloroform, according to Journal of Biological Chemistry, 248, 40186-40197 (2003).

  7. What are some of the physical properties of Product No. 40227 (6-Dodecanoyl-N,N-dimethyl-2-naphthylamine, also known as Laurdan)?

    The physical properties of  6-Dodecanoyl-N,N-dimethyl-2-naphthylamine are:Boiling Point: 497.4 °C at atmospheric pressure (760 mm Hg)Flash Point: 177.4 °CMelting Point: 88°C(lit.)Density: 0.987 g/cm3Vapor Pressure: 4.95-10 mm Hg at 25°CRefractive Index: 1.553

  8. What are the spectral properties (excitation and emission maxima) of 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine, Laurdan, Product 40227?

    The spectral properties of 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine are: ?ex 366 nm; ?em 497 nm in methanol.

  9. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Keita Hayashi et al.
Colloids and surfaces. B, Biointerfaces, 87(1), 28-35 (2011-05-31)
The surface properties of Span 80 vesicles at various cholesterol contents, together with those of various liposomes, were characterized by using fluorescence probes. The membrane fluidity of the Span 80 vesicles was measured by 1,6-diphenyl-1.3.5-hexatriene (DPH) and trimethlyammonium-DPH (TMA-DPH), and
Simmon Hofstetter et al.
Journal of microbiological methods, 91(1), 93-100 (2012-08-14)
A method for measuring the fluidity of inner membranes of populations of endospores of Clostridium spp. with a fluorescent dye was developed. Cells of Clostridium beijerinckii ATCC 8260 and Clostridium sporogenes ATCC 7955 were allowed to sporulate in the presence
L.I. Hellgren
Plant Physiology and Biochemistry, 34, 455-455 (1996)
L A Bagatolli et al.
Biochimica et biophysica acta, 1325(1), 80-90 (1997-04-03)
Laurdan (6-dodecanoyl-2-dimethylamine-naphthalene) is a fluorescent membrane probe of recent characterization. It was shown that this probe discriminates between phase transitions, phase fluctuations and the coexistence of phase domains in phospholipid multilamellar aggregates. We measured the excitation and emission generalized polarization
Adéla Melcrová et al.
Scientific reports, 6, 38035-38035 (2016-12-03)
Understanding interactions of calcium with lipid membranes at the molecular level is of great importance in light of their involvement in calcium signaling, association of proteins with cellular membranes, and membrane fusion. We quantify these interactions in detail by employing
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