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40227

6-十二酰基- N,N -二甲基-2-萘胺

Name: 6-十二酰基-<I> N,N </I>-二甲基-2-萘胺
Brand: SIGMA

suitable for fluorescence, ≥97.0% (HPLC)

别名:

2-（二甲氨基）-6-十二酰萘, N,N-二甲基-6-十二酰-2-萘胺, 劳丹

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关于此项目

经验公式（希尔记法）:

C₂₄H₃₅NO

化学文摘社编号:

74515-25-6

分子量:

353.54

UNSPSC Code:

12352116

NACRES:

NA.32

PubChem Substance ID:

57649941

MDL number:

MFCD00467560

Beilstein/REAXYS Number:

7379104

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Quality Level

100

assay

≥97.0% (HPLC)

mp

88 °C (lit.)

solubility

DMF: soluble, acetonitrile: soluble, methanol: soluble

fluorescence

λ_ex 366 nm; λ_em 497 nm in methanol

suitability

suitable for fluorescence

SMILES string

CCCCCCCCCCCC(=O)c1ccc2cc(ccc2c1)N(C)C

InChI

1S/C24H35NO/c1-4-5-6-7-8-9-10-11-12-13-24(26)22-15-14-21-19-23(25(2)3)17-16-20(21)18-22/h14-19H,4-13H2,1-3H3

InChI key

JHDGGIDITFLRJY-UHFFFAOYSA-N

Application

6-十二酰基- N,N -二甲基-2-萘胺 (Laurdan) 是一种用于研究膜结构、顺序和流动性等动态过程的荧光探针。

Packaging

无底玻璃瓶。内含物装在插入的融合锥内。

Other Notes

荧光膜探针

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Span 80 vesicles have a more fluid, flexible and "wet" surface than phospholipid liposomes.

Keita Hayashi et al.

Colloids and surfaces. B, Biointerfaces, 87(1), 28-35 (2011-05-31)

The surface properties of Span 80 vesicles at various cholesterol contents, together with those of various liposomes, were characterized by using fluorescence probes. The membrane fluidity of the Span 80 vesicles was measured by 1,6-diphenyl-1.3.5-hexatriene (DPH) and trimethlyammonium-DPH (TMA-DPH), and

L.I. Hellgren

Plant Physiology and Biochemistry, 34, 455-455 (1996)

Lipoprotein hydrophobic core lipids are partially extruded to surface in smaller HDL: "Herniated" HDL, a common feature in diabetes.

Núria Amigó et al.

Scientific reports, 6, 19249-19249 (2016-01-19)

Recent studies have shown that pharmacological increases in HDL cholesterol concentrations do not necessarily translate into clinical benefits for patients, raising concerns about its predictive value for cardiovascular events. Here we hypothesize that the size-modulated lipid distribution within HDL particles

Laurdan properties in glycosphingolipid-phospholipid mixtures: a comparative fluorescence and calorimetric study.

L A Bagatolli et al.

Biochimica et biophysica acta, 1325(1), 80-90 (1997-04-03)

Laurdan (6-dodecanoyl-2-dimethylamine-naphthalene) is a fluorescent membrane probe of recent characterization. It was shown that this probe discriminates between phase transitions, phase fluctuations and the coexistence of phase domains in phospholipid multilamellar aggregates. We measured the excitation and emission generalized polarization

Use of the fluorescent probe LAURDAN to label and measure inner membrane fluidity of endospores of Clostridium spp.

Simmon Hofstetter et al.

Journal of microbiological methods, 91(1), 93-100 (2012-08-14)

A method for measuring the fluidity of inner membranes of populations of endospores of Clostridium spp. with a fluorescent dye was developed. Cells of Clostridium beijerinckii ATCC 8260 and Clostridium sporogenes ATCC 7955 were allowed to sporulate in the presence

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全球贸易项目编号

货号	GTIN
40227-100MG	04061833646359

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