40674
松脂醇
≥95.0% (HPLC)
别名:
(+)-松脂醇, 4,4′-((1S,3aR,4S,6aR)-六氢呋喃[3,4-c]呋喃-1,4-二基)双(2-甲氧基苯酚), 4,4′-[(1S,3aR,4S,6aR)-四氢-1H,3H-呋喃[3,4-c]呋喃-1,4-二基]双(2-甲氧基苯酚) )
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关于此项目
经验公式（希尔记法）:
C20H22O6
化学文摘社编号:
分子量:
358.39
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352205
MDL number:
Quality Segment
assay
≥95.0% (HPLC)
form
powder or crystals
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
SMILES string
COc1cc(ccc1O)[C@H]2OC[C@H]3[C@@H]2CO[C@@H]3c4ccc(O)c(OC)c4
InChI
1S/C20H22O6/c1-23-17-7-11(3-5-15(17)21)19-13-9-26-20(14(13)10-25-19)12-4-6-16(22)18(8-12)24-2/h3-8,13-14,19-22H,9-10H2,1-2H3/t13-,14-,19+,20+/m0/s1
InChI key
HGXBRUKMWQGOIE-AFHBHXEDSA-N
General description
Pinoresinol is a secondary metabolite, a lignan found in wide varieties of plants. Structurally, it is one of the simple lignans, with a dimer of coniferyl alcohol, which forms the bicyclic ring core.
Application
Pinoresinol has been used:
- as a reference standard for qualitative and quantitative analysis of lignans from Triticale (X Triticosecale Wittmack) grains using ultra-performance liquid chromatography (UPLC) with photodiode and mass TQD detectors
- as an enterolignan precursor to study its estrogenic activity on the proliferation of human breast cancer MCF-7 cells
- as a reference standard for lignan analysis of Sesamum indicum L. seeds
Biochem/physiol Actions
松脂素存在于包括药用植物在内的多种植物中，如水生接骨木、杜仲、安息香属、连翘以及特级初榨橄榄油中。其中的接骨木属广泛分布于欧洲、亚洲和北非，并已在传统医学中作为止痛药、抗病毒药、抗炎药、止血药和利尿药用于瘀伤、骨折和水肿。松脂素可通过引起真菌质膜的损伤而显示出有效的抗真菌特性。它通过抑制TNF-α的产生（很可能是通过抑制NF- κB和AP-1）而发挥出抗氧化和抗炎的作用。
通过抑制TNF-α的产生而发挥出抗氧化和抗炎的作用。
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable