41525
N,N-Dimethyl-6-propionyl-2-naphthylamine
BioReagent, suitable for fluorescence, ≥98.0% (HPLC)
别名:
2-(Dimethylamino)-6-propionylnaphthalene, 6-Propionyl-2-(dimethylamino)naphthalene, Prodan
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关于此项目
经验公式（希尔记法）:
C15H17NO
CAS Number:
分子量:
227.30
Beilstein:
2723587
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.32
产品线
BioReagent
质量水平
方案
≥98.0% (HPLC)
表单
solid
mp
137 °C (lit.)
溶解性
DMF: soluble
acetone: soluble
acetonitrile: soluble
methanol: soluble
荧光
λex 361 nm; λem 498 nm in methanol
适用性
suitable for fluorescence
SMILES字符串
CCC(=O)c1ccc2cc(ccc2c1)N(C)C
InChI
1S/C15H17NO/c1-4-15(17)13-6-5-12-10-14(16(2)3)8-7-11(12)9-13/h5-10H,4H2,1-3H3
InChI key
MPPQGYCZBNURDG-UHFFFAOYSA-N
应用
N,N-Dimethyl-6-propionyl-2-naphthylamine (Prodan), a membrane surface probe, may be used as a fluorescence probe in non-cell based in vitro assay for the determination of drug-phospholipid complex formation and to study membrane surface properties.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
其他说明
Fluorescence of spectrin-bound Prodan
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
A Chakrabarti
Biochemical and biophysical research communications, 226(2), 495-497 (1996-09-13)
A large blue-shift (delta lambda max = 87 nm) in the fluorescence emission maximum and 2-fold enhancement in the emission intensity of PRODAN in the presence of 1.5 microM dimeric spectrin from the same aqueous buffer was observed. Binding of
Liping Zhou et al.
Analytical chemistry, 83(18), 6980-6987 (2011-07-28)
This paper describes for the first time, a high-throughput fluorescence noncell based assay to screen for the drug-phospholipid interaction, which correlates to phospholipidosis. Anionic amphiphilic phospholipids can form complexes in aqueous solution, and its critical micelle concentration (CMC) can be
Praveen Gadad et al.
Water research, 41(19), 4488-4496 (2007-07-17)
Noncovalent interactions between the fluorescent probe 6-propionyl-2-dimethylaminonaphthalene (PRODAN) and dissolved Norman Landfill leachate fulvic acid, Suwannee River fulvic acid, Suwannee River humic acid, and Leonardite humic acid were examined as a function of pH, fulvic and humic acid (FA and
Kazuki Tainaka et al.
Journal of the American Chemical Society, 129(15), 4776-4784 (2007-03-24)
A solvatochromic fluorophore, PRODAN, has been used as a microenvironment-sensitive reporter. Based on the chemistry of PRODAN, we designed and synthesized four novel fluorescent nucleosides, PDNX (X = U, C, A, and G), to which a PRODAN fluorophore was attached
Ramkrishna Adhikary et al.
The journal of physical chemistry. B, 113(35), 11999-12004 (2009-08-28)
The coexistence of different excited states with different properties of the same chromophores could have significant consequences for the accurate characterization of solvation dynamics in a heterogeneous environment, such as a protein. The purpose of this work is to study
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