41525
N,N-Dimethyl-6-propionyl-2-naphthylamine
BioReagent, suitable for fluorescence, ≥98.0% (HPLC)
别名:
2-(Dimethylamino)-6-propionylnaphthalene, 6-Propionyl-2-(dimethylamino)naphthalene, Prodan
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关于此项目
经验公式（希尔记法）:
C15H17NO
化学文摘社编号:
分子量:
227.30
UNSPSC Code:
12352116
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2723587
InChI
1S/C15H17NO/c1-4-15(17)13-6-5-12-10-14(16(2)3)8-7-11(12)9-13/h5-10H,4H2,1-3H3
SMILES string
CCC(=O)c1ccc2cc(ccc2c1)N(C)C
InChI key
MPPQGYCZBNURDG-UHFFFAOYSA-N
product line
BioReagent
assay
≥98.0% (HPLC)
form
solid
Quality Level
solubility
DMF: soluble, acetone: soluble, acetonitrile: soluble, methanol: soluble
fluorescence
λex 361 nm; λem 498 nm in methanol
suitability
suitable for fluorescence
Application
N,N-Dimethyl-6-propionyl-2-naphthylamine (Prodan), a membrane surface probe, may be used as a fluorescence probe in non-cell based in vitro assay for the determination of drug-phospholipid complex formation and to study membrane surface properties.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Fluorescence of spectrin-bound Prodan
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Liping Zhou et al.
Analytical chemistry, 83(18), 6980-6987 (2011-07-28)
This paper describes for the first time, a high-throughput fluorescence noncell based assay to screen for the drug-phospholipid interaction, which correlates to phospholipidosis. Anionic amphiphilic phospholipids can form complexes in aqueous solution, and its critical micelle concentration (CMC) can be
A Chakrabarti
Biochemical and biophysical research communications, 226(2), 495-497 (1996-09-13)
A large blue-shift (delta lambda max = 87 nm) in the fluorescence emission maximum and 2-fold enhancement in the emission intensity of PRODAN in the presence of 1.5 microM dimeric spectrin from the same aqueous buffer was observed. Binding of
Praveen Gadad et al.
Water research, 41(19), 4488-4496 (2007-07-17)
Noncovalent interactions between the fluorescent probe 6-propionyl-2-dimethylaminonaphthalene (PRODAN) and dissolved Norman Landfill leachate fulvic acid, Suwannee River fulvic acid, Suwannee River humic acid, and Leonardite humic acid were examined as a function of pH, fulvic and humic acid (FA and
Kazuki Tainaka et al.
Journal of the American Chemical Society, 129(15), 4776-4784 (2007-03-24)
A solvatochromic fluorophore, PRODAN, has been used as a microenvironment-sensitive reporter. Based on the chemistry of PRODAN, we designed and synthesized four novel fluorescent nucleosides, PDNX (X = U, C, A, and G), to which a PRODAN fluorophore was attached
Paul Abbyad et al.
The journal of physical chemistry. B, 111(28), 8269-8276 (2007-06-27)
Proteins respond to electrostatic perturbations through complex reorganizations of their charged and polar groups, as well as those of the surrounding media. These solvation responses occur both in the protein interior and on its surface, though the exact mechanisms of
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