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Merck
CN

41785

溴化二亚胺

BioReagent, suitable for fluorescence, ~95% (AT)

别名:

3,8-二氨基-5-甲基-6-苯基菲啶鎓溴化物, 胰蛋白酶, 菲啶盐1553

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关于此项目

经验公式(希尔记法):
C20H18BrN3
化学文摘社编号:
分子量:
380.28
UNSPSC Code:
12171500
NACRES:
NA.32
PubChem Substance ID:
EC Number:
208-256-7
Beilstein/REAXYS Number:
3809779
MDL number:
Assay:
~95% (AT)
Form:
solid
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product line

BioReagent

Quality Level

assay

~95% (AT)

form

solid

mol wt

380.28 g/mol

concentration

80-100 % (w/w) (3,8-Diamino-5-methyl-6-phenylphenanthridinium bromide)

color

dark purple to very dark purple, dark red to very dark red

mp

243-248 °C (lit.)

fluorescence

λex 306 nm; λem 612 nm in 50 mM Tris pH 8.0 (DNA), λex 480 (pH 7.6, low ionic strength)

suitability

suitable for fluorescence

SMILES string

[Br-].C[n+]1c(-c2ccccc2)c3cc(N)ccc3c4ccc(N)cc14

InChI

1S/C20H17N3.BrH/c1-23-19-12-15(22)8-10-17(19)16-9-7-14(21)11-18(16)20(23)13-5-3-2-4-6-13;/h2-12,22H,21H2,1H3;1H

InChI key

MQOKYEROIFEEBH-UHFFFAOYSA-N

General description

溴甲菲啶是一种抗锥虫药物,已知它可在许多生物体中影响核酸合成,比如组织培养的细胞。

Application

基于碱基对的特异性,溴甲菲啶被用作天然DNA的粘合剂。它在核酸实验中用作荧光剂。
核酸插入探针。


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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相关内容

Nancy-520 for DNA Detection and Quantitation


Nuclear transplantation studies of the action of dimidium bromide on amoebae.
S E Hawkins et al.
Nature, 222(5188), 86-87 (1969-04-05)
G Dougherty
The International journal of biochemistry, 14(6), 493-504 (1982-01-01)
1. The absorption spectrum of three phenanthridine drugs (ethidium, dimidium and prothidium bromide) bound to natural DNAs of differing G-C content were obtained using a novel mixing scheme and analysed according to the excluded site binding model. 2. Ethidium bromide
T P Mozhenok et al.
Tsitologiia, 40(6), 585-590 (1998-10-21)
Effect of DNA-intercalators ethidium bromide (EB, 0.005 and 0.015 mM) and dimidium bromide (DB, 0.005 and 0.010 mM) and antioxidative compounds acetylsalicylic acid (ASA, 0.05 and 0.50 mM) and beta-carotene (0.01, 0.02, 0.05 mM) on the phagosome-lysosome (P-L) fusion and



全球贸易项目编号

货号GTIN
41785-250MG04061835570546
41785-1G04061835570539