41969
5-羧基-X-罗丹明 N -琥珀酰亚胺酯
BioReagent, suitable for fluorescence
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关于此项目
经验公式（希尔记法）:
C37H33N3O7
化学文摘社编号:
分子量:
631.67
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352116
MDL number:
产品名称
5-羧基-X-罗丹明 N -琥珀酰亚胺酯, BioReagent, suitable for fluorescence
InChI
1S/C37H33N3O7/c41-29-11-12-30(42)40(29)47-37(45)22-9-10-23(26(19-22)36(43)44)31-27-17-20-5-1-13-38-15-3-7-24(32(20)38)34(27)46-35-25-8-4-16-39-14-2-6-21(33(25)39)18-28(31)35/h9-10,17-19H,1-8,11-16H2
SMILES string
[O-]C(=O)c1cc(ccc1-c2c3cc4CCCN5CCCc(c45)c3[o+]c6c7CCCN8CCCc(cc26)c78)C(=O)ON9C(=O)CCC9=O
InChI key
BTTBJYLMDASSAS-UHFFFAOYSA-N
product line
BioReagent
form
powder
solubility
DMF: soluble
acetonitrile: soluble
fluorescence
λex 575 nm; λem 600 nm in 0.1 M phosphate pH 7.0
suitability
suitable for fluorescence
storage temp.
−20°C
Quality Level
Application
5-羧基-X-罗丹明N-琥珀酰亚胺酯（ROX-SE）被用作胺偶联剂，形成5-羧基-X-罗丹明（ROX）衍生化合物，如蛋白质、核酸和药物，可通过荧光共振能量转移（FRET）和荧光猝灭应用对它们进行分析。作为标记试剂用于制备电荷修饰的染料标记ddNTPs，以供“直接加载”DNA测序使用。
Other Notes
作为标记试剂用于制备电荷修饰的染料标记ddNTPs，以供“直接加载”DNA测序使用
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Jonathan F Lovell et al.
Journal of the American Chemical Society, 133(46), 18580-18582 (2011-10-27)
Photodynamic therapy (PDT) stands to benefit from improved approaches to real-time treatment monitoring. One method is to use activatable photosensitizers that can both induce cell death (via singlet oxygen) and monitor it (via caspase detection). Here, we report porphyrins as
Yunfeng Xia et al.
The Analyst, 137(24), 5705-5709 (2012-10-27)
We report a sensitive approach for SERS detection of cytochrome c using target binding-induced conformational changes of signal transduction probe (STP). STP labeled with a SERS-active molecule, carboxy-X-rhodamine (ROX), is immobilized on the substrate where the formation of a rigid
Patrick J Finn et al.
Nucleic acids research, 30(13), 2877-2885 (2002-06-28)
A novel series of charge-modified, dye-labeled 2',3'-dideoxynucleoside-triphosphate terminators were synthesized and evaluated as reagents for DNA sequencing. These terminators possess an advantage over existing reagents in that no purification is required to remove unreacted nucleotide or associated breakdown products prior
Ting Qiu et al.
The Analyst, 135(9), 2394-2399 (2010-08-03)
A new strategy for quantitatively detecting micrococcal nuclease (MNase) is proposed using electrostatic interaction-based fluorescence resonance energy transfer (FRET) between positively charged QDs and negatively charged dye-labeled single-stranded DNA (dye-ssDNA). Herein, we have made our attempt to develop a strategy
Xia Xiang et al.
Analytica chimica acta, 751, 155-160 (2012-10-23)
The development of simple and inexpensive DNA detection strategy is very significant for droplet-based microfluidic system. Here, a droplet-based biosensor for multiplexed DNA analysis is developed with a common imaging device by using fluorescence-based colorimetric method and a graphene nanoprobe.
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