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426R-1

STAT6 (EP325) Rabbit Monoclonal Primary Antibody

Name: STAT6 (EP325) Rabbit Monoclonal Primary Antibody
Brand: SIGMA

别名:

Signal Transducer and Activator of Transcription

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关于此项目

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

EP325, monoclonal

Application:

IHC (p)

Citations:

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属性

biological source

rabbit

Quality Segment

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EP325, monoclonal

description

For In Vitro Diagnostic Use in Select Regions

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (426R-14), vial of 0.1 mL concentrate Research Use Only (426R-14-RUO), vial of 0.5 mL concentrate (426R-15), vial of 1.0 mL concentrate (426R-16), vial of 1.0 mL concentrate Research Use Only (426R-16-RUO), vial of 1.0 mL pre-dilute Research Use Only (426R-17-RUO), vial of 1.0 mL pre-dilute ready-to-use (426R-17), vial of 7.0 mL pre-dilute ready-to-use (426R-18), vial of 7.0 mL pre-dilute ready-to-use Research Use Only (426R-18-RUO)

manufacturer/tradename

Cell Marque^®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)

isotype

IgG

control

solitary fibrous tumor

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Gene Information

human ... STAT6(6778)

说明

General description

STAT6, a member of the signal transducers and activators of transcription (STAT) family, has been found to form recurrent fusions with NAB2 on chromosome 12q13 in the majority of solitary fibrous tumors. Inactivated STAT6 can be found in the form of a dimer located in the cytoplasm. STAT6 and NAB2 fusion enables cytosolic STAT6 to migrate to the nucleus and thus allowing for detection in immunohistochemical assays. NAB2-STAT6 fusion transcriptions have been reported in the majority of solitary fibrous tumors but not in meningiomas, hemangioblastomas, schwannomas, and hemangiomas. This makes STAT6 a useful marker in distinguishing solitary fibrous tumors from other morphologically similar tumors.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Analysis Note

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c