42945
(−)-Hydroxymatairesinol, mixture of epimers
≥90% (HPLC)
别名:
(3R,4R)-Dihydro-4-[hydroxy(4-hydroxy-3-methoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone, 7-Hydroxymatairesinol-7-allo-Hydroxymatairesinol mixture
产品名称
(−)-Hydroxymatairesinol, mixture of epimers, ≥90% (HPLC)
InChI
1S/C20H22O7/c1-25-16-8-11(3-5-14(16)21)7-13-10-27-20(24)18(13)19(23)12-4-6-15(22)17(9-12)26-2/h3-6,8-9,13,18-19,21-23H,7,10H2,1-2H3/t13-,18+,19?/m0/s1
InChI key
ZZSOKNNVDKKSDE-HDOPWBOFSA-N
SMILES string
COc1cc(C[C@H]2COC(=O)[C@H]2C(O)c3ccc(O)c(OC)c3)ccc1O
assay
≥90% (HPLC)
Application
This product is an epimeric mixture of hydroxymatairesinol, a plant phytoestrogen, which may be used to study its proestrogenic, antioxidant and chemopreventative properties.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Aquatic Acute 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Marco Cosentino et al.
Pharmacological research, 56(2), 140-147 (2007-06-19)
Lignans are plant polyphenols which may possess anticancer, antioxidant, antimicrobial, anti-inflammatory and immunomodulatory activities. In particular, the lignan 7-hydroxymatairesinol (HMR/lignan, HMR) is a novel precursor of the mammalian lignan enterolactone (EL). In the present study, we investigated the estrogenicity of
Daiki Miura et al.
Nutrition and cancer, 58(1), 49-59 (2007-06-19)
Both epidemiological and experimental evidence is accumulating to show that a lignan-rich diet may reduce the risk of human breast cancer. Possible anti-cancer effects of dietary lignans on hepatomas or hepatoma cells have not been the topic of earlier studies.
Marco Cosentino et al.
International immunopharmacology, 10(3), 339-343 (2009-12-17)
The pharmacological profile of the lignan 7-hydroxymatairesinol (HMR/lignan, HMR) includes chemopreventive effects, antioxidant properties, and mild proestrogenic activity. The present study was devised to investigate the effects of HMR on THP-1 cells, an established model of human monocytes, and on
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