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Merck
CN

43307

1,2-二硬脂酰-sn-甘油基-3-磷酸- L -丝氨酸 钠盐

≥75% (TLC)

别名:

1,2-二十八烷酰基-sn-甘油-3-磷酸-L-丝氨酸 钠盐, 3-sn-磷脂酰-L-丝氨酸,二硬脂酰基 钠盐, DSPS-Na, PS(18:0/18:0)

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关于此项目

经验公式(希尔记法):
C42H81NNaO10P
化学文摘社编号:
分子量:
814.06
NACRES:
NA.85
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
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InChI key

SJRBMGBLPUBGJL-MBAWARMDSA-M

SMILES string

[Na+].CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C42H82NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h38-39H,3-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/t38-,39+;/m1./s1

biological source

synthetic

assay

≥75% (TLC)

form

crystalline

functional group

carboxylic acid

lipid type

phosphoglycerides

storage temp.

−20°C

Application

在胆固醇-磷脂混合物的相变研究中,胆固醇在凝胶相中与DSPS的混溶性要比液晶相中弱得多;最高50 mol%的胆固醇并不能消除烃链熔融相变。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Richard H Carson et al.
Journal of lipid research, 58(9), 1884-1892 (2017-07-27)
Compartmentalization of metabolism into specific regions of the cell, tissue, and organ is critical to life for all organisms. Mass spectrometric imaging techniques have been valuable in identifying and quantifying concentrations of metabolites in specific locations of cells and tissues
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Journal of applied biomaterials & functional materials, 18, 2280800020942712-2280800020942712 (2020-11-06)
A neurodegenerative disorder, glaucoma is a leading cause of blindness in the world. The conventional treatment strategies do not allow the significant penetration of the drug in the cornea. Therefore, we prepare a brinzolamide (Brz) loaded core-shell nanoparticles (NPs) to
Filippo Caschera et al.
PloS one, 5(1), e8546-e8546 (2010-01-06)
We consider the problem of optimizing a liposomal drug formulation: a complex chemical system with many components (e.g., elements of a lipid library) that interact nonlinearly and synergistically in ways that cannot be predicted from first principles. The optimization criterion
Monika Naumowicz et al.
Membranes, 10(11) (2020-11-19)
Pharmacological efficiency of active compounds is largely determined by their membrane permeability. Thus, identification of drug-membrane interactions seems to be a crucial element determining drug-like properties of chemical agents. Yet, knowledge of this issue is still lacking. Since chemoprevention based
Stephanie Jemielity et al.
PLoS pathogens, 9(3), e1003232-e1003232 (2013-04-05)
Human T-cell Immunoglobulin and Mucin-domain containing proteins (TIM1, 3, and 4) specifically bind phosphatidylserine (PS). TIM1 has been proposed to serve as a cellular receptor for hepatitis A virus and Ebola virus and as an entry factor for dengue virus.

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