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Merck
CN

43608

3,3ˊ-二丙基硫杂二羰花青碘化物

suitable for fluorescence, ≥98.0% (TLC)

别名:

3-丙基-2-[5-[3-丙基-2(3H)-苯并噻唑基]-1,3-戊二烯基]苯并噻唑鎓碘化物, DiSC3(5)

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关于此项目

经验公式（希尔记法）:
C25H27IN2S2
化学文摘社编号:
53213-94-8
分子量:
546.53
MDL编号:
MFCD00075033
UNSPSC代码:
12352116
PubChem化学物质编号:
57650184
NACRES:
NA.32

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质量水平

100

方案

≥98.0% (TLC)

表单

powder

mp

245 °C (dec.) (lit.)

溶解性

DMF: soluble

荧光

λex 500 nm; λem 705 nm in DMF

适用性

suitable for fluorescence

SMILES字符串

[I-].CCCN1C(\Sc2ccccc12)=C\C=C\C=C\c3sc4ccccc4[n+]3CCC

InChI

1S/C25H27N2S2.HI/c1-3-18-26-20-12-8-10-14-22(20)28-24(26)16-6-5-7-17-25-27(19-4-2)21-13-9-11-15-23(21)29-25;/h5-17H,3-4,18-19H2,1-2H3;1H/q+1;/p-1

InChI key

GDEURKKLNUGTDA-UHFFFAOYSA-M

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相关类别

应用

碘化-3,3′-二丙基硫杂二羰花青[DiSC3(5)]可用作荧光探针，以检测和测量由膜改变剂诱导的跨膜电位或构型的变化。

包装

无底玻璃瓶。内容物在插入式融锥内。

其他说明

跨膜电位测量

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCM6510
BCCK8898
BCCH6675
BCCG3331
BCCD6948

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M Síp et al.
Journal of photochemistry and photobiology. B, Biology, 4(3), 321-328 (1990-01-01)
The mechanism of carbocyanine dye diS-C3-(5) fluorescence intensity variations with transmembrane potential changes has been studied using time-resolved fluorescence spectroscopy. Clear evidence is given of the transmembrane-potential-dependent partition of the dye among various sites with different fluorescence lifetimes. It was
Min Kyoung Shin et al.
Antibiotics (Basel, Switzerland), 9(7) (2020-07-28)
The prevalence of antibiotic-resistant bacteria has become an immediate threat to public health. Antimicrobial peptides are attracting attention as a new source of antibiotics due to their ability to prevent drug-resistances with fewer side effects. Spider venom is composed of
Wen Ma et al.
Journal of proteomics, 150, 242-251 (2016-10-25)
Daptomycin (DAP) is a novel lipopeptide antibiotic which exhibits excellent antibacterial activity against most clinically relevant Gram-positive bacteria, but the DAP-targeting protein molecules against host bacterial infection are far from clear. In order to discover bacterial protein response to DAP
Venkateswarlu Yarlagadda et al.
Scientific reports, 10(1), 8134-8134 (2020-05-20)
Despite the remarkable advances due to the discovery and development of antimicrobials agents, infectious diseases remain the second leading cause of death worldwide. This fact underlines the importance of developing new therapeutic strategies to address the widespread antibiotic resistance, which
Ting-Wei Chang et al.
PloS one, 12(10), e0186442-e0186442 (2017-10-19)
Antimicrobial peptides are important components of the host innate defense mechanism against invading pathogens, especially for drug-resistant bacteria. In addition to bactericidal activity, the 25 residue peptide TP4 isolated from Nile tilapia also stimulates cell proliferation and regulates the innate
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