43608
3,3ˊ-二丙基硫杂二羰花青碘化物
suitable for fluorescence, ≥98.0% (TLC)
别名:
3-丙基-2-[5-[3-丙基-2(3H)-苯并噻唑基]-1,3-戊二烯基]苯并噻唑鎓碘化物, DiSC3(5)
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关于此项目
经验公式（希尔记法）:
C25H27IN2S2
化学文摘社编号:
分子量:
546.53
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352116
MDL number:
InChI
1S/C25H27N2S2.HI/c1-3-18-26-20-12-8-10-14-22(20)28-24(26)16-6-5-7-17-25-27(19-4-2)21-13-9-11-15-23(21)29-25;/h5-17H,3-4,18-19H2,1-2H3;1H/q+1;/p-1
SMILES string
[I-].CCCN1C(\Sc2ccccc12)=C\C=C\C=C\c3sc4ccccc4[n+]3CCC
InChI key
GDEURKKLNUGTDA-UHFFFAOYSA-M
assay
≥98.0% (TLC)
form
powder
mp
245 °C (dec.) (lit.)
solubility
DMF: soluble
fluorescence
λex 500 nm; λem 705 nm in DMF
suitability
suitable for fluorescence
Quality Level
Application
碘化-3,3′-二丙基硫杂二羰花青[DiSC3(5)]可用作荧光探针，以检测和测量由膜改变剂诱导的跨膜电位或构型的变化。
Packaging
无底玻璃瓶。内容物在插入式融锥内。
Other Notes
跨膜电位测量
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Wen Ma et al.
Journal of proteomics, 150, 242-251 (2016-10-25)
Daptomycin (DAP) is a novel lipopeptide antibiotic which exhibits excellent antibacterial activity against most clinically relevant Gram-positive bacteria, but the DAP-targeting protein molecules against host bacterial infection are far from clear. In order to discover bacterial protein response to DAP
Min Kyoung Shin et al.
Antibiotics (Basel, Switzerland), 9(7) (2020-07-28)
The prevalence of antibiotic-resistant bacteria has become an immediate threat to public health. Antimicrobial peptides are attracting attention as a new source of antibiotics due to their ability to prevent drug-resistances with fewer side effects. Spider venom is composed of
M Síp et al.
Journal of photochemistry and photobiology. B, Biology, 4(3), 321-328 (1990-01-01)
The mechanism of carbocyanine dye diS-C3-(5) fluorescence intensity variations with transmembrane potential changes has been studied using time-resolved fluorescence spectroscopy. Clear evidence is given of the transmembrane-potential-dependent partition of the dye among various sites with different fluorescence lifetimes. It was
Sonya E Neal et al.
Molecular biology of the cell, 28(21), 2773-2785 (2017-08-18)
Prokaryotes have aerobic and anaerobic electron acceptors for oxidative folding of periplasmic proteins. The mitochondrial intermembrane space has an analogous pathway with the oxidoreductase Mia40 and sulfhydryl oxidase Erv1, termed the mitochondrial intermembrane space assembly (MIA) pathway. The aerobic electron
Marie Markones et al.
Biophysical journal, 118(2), 294-302 (2019-12-18)
Membrane proteins are embedded in a complex lipid environment that influences their structure and function. One key feature of nearly all biological membranes is a distinct lipid asymmetry. However, the influence of membrane asymmetry on proteins is poorly understood, and
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